Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.58 |
| ▸ | PGR | P06401 | 6/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.58 |
| ▸ | AR | P10275 | 6/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027911 | 0.80 | SLC22A12 (0.63) | NR3C1PGRNR3C2ARSLC22A12 | |
| SCHEMBL4860020 | 0.77 | PTGS1 (0.63) | NR3C1PGRNR3C2ARSLC22A12 | |
| SCHEMBL13848266 | 0.76 | L3MBTL1 (0.54) | NR3C1PGRNR3C2ARSLC22A12 | |
| SCHEMBL8940603 | 0.74 | ERN1 (0.51) | NR3C1PGRNR3C2ARCDK9 | |
| SCHEMBL8524487 | 0.74 | PTGS2 (0.59) | NR3C1PGRNR3C2ARPTGS1 | |
| SCHEMBL20523653 | 0.73 | SLC22A12 (0.48) | NR3C1PGRNR3C2ARSLC22A12 | |
| SCHEMBL28444470 | 0.72 | SLC22A12 (1.00) | NR3C1PGRNR3C2ARSLC22A12 | |
| SCHEMBL31090892 | 0.71 | PTGS1 (0.55) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL4620558 | 0.71 | JAK2 (0.52) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL3347567 | 0.71 | HTR7 (0.47) | NR3C1NR3C2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210244717-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | NR3C1 3083/4885PGR 1996/4885NR3C2 1932/4885 |
| US-20210244717-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | NR3C1 3309/4885PGR 2952/4885NR3C2 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.