Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 9/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803701 | 0.82 | ALDH1A1 (0.42) | ALDH1A1ALOX15KMT2AMEN1POLB | |
| SCHEMBL1807706 | 0.81 | GRM1 (0.40) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL20537201 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TDP1CES2CES1KMT2A | |
| SCHEMBL8702458 | 0.74 | CES2 (0.59) | ALDH1A1ALOX15CES2CES1BCHE | |
| SCHEMBL104744 | 0.73 | CES2 (0.68) | ALDH1A1ALOX15TDP1CES2CES1 | |
| SCHEMBL21965336 | 0.72 | CTNNB1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL1422986 | 0.71 | CES2 (0.65) | ALDH1A1ALOX15TDP1CES2CES1 | |
| SCHEMBL9836255 | 0.71 | ALDH1A1 (0.65) | ALDH1A1ALOX15TDP1CES2CES1 | |
| SCHEMBL19185970 | 0.71 | ALDH1A1 (0.62) | ALDH1A1ALOX15TDP1CES2CES1 | |
| SCHEMBL1802624 | 0.70 | ACLY (0.43) | ALDH1A1ALOX15KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392236-B1 | METHOD FOR PRODUCING AROMATIC AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO INC (JP) | 2021-06-23 | — | — | EP | disclosed |
| CN-108368030-B | Process for producing aromatic amide derivative | 三井化学AGRO株式会社 | 2020-09-18 | — | — | CN | disclosed |
| US-10647660-B2 | Method of producing aromatic amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-05-12 | — | — | US | disclosed |
| US-20180362447-A1 | METHOD OF PRODUCING AROMATIC AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3392236-A1 | METHOD FOR PRODUCING AROMATIC AMIDE DERIVATIVE | Mitsui Chemicals Agro, Inc. (JP) | 2018-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362447-A1 | METHOD OF PRODUCING AROMATIC AMIDE DERIVATIVE | HDHD5, NAAA, H1-4 | ALDH1A1 461/4885ALOX15 3173/4885TDP1 2952/4885 |
| US-10647660-B2 | Method of producing aromatic amide derivative | HDHD5, NAAA, H1-4 | ALDH1A1 461/4885ALOX15 3173/4885TDP1 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.