Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 11/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.33 |
| ▸ | MEN1 | O00255 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.33 |
| ▸ | TP53 | P04637 | 6/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209384 | 0.80 | POLB (0.62) | SMN1; SMN2POLBHSD17B10KDM4ELMNA | |
| SCHEMBL9024048 | 0.79 | LMNA (0.45) | SMN1; SMN2POLBHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL3202848 | 0.79 | MTNR1A (0.48) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL6195388 | 0.77 | KMT2A (0.38) | SMN1; SMN2POLBHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL18297785 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2POLBALDH1A1KDM4ELMNA | |
| SCHEMBL5785927 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2POLBHSD17B10NPSR1KDM4E | |
| SCHEMBL182827 | 0.77 | MAPT (0.46) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL2458803 | 0.76 | TUBB1 (0.41) | SMN1; SMN2POLBHSD17B10ALDH1A1LMNA | |
| SCHEMBL8674 | 0.75 | CA2 (0.46) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL9024831 | 0.75 | ALDH1A1 (0.54) | SMN1; SMN2POLBHSD17B10NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199087-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ROWAN UNIVERSITY | 2020-06-25 | — | — | US | claimed |
| EP-3625200-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | Rowan University (US) | 2020-03-25 | — | — | EP | claimed |
| WO-2018213236-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ROWAN UNIVERSITY (US) | 2018-11-22 | — | — | WO | claimed |
| US-11008297-B2 | Bio-based, multi-aromatic compounds, and methods of making and using same | ROWAN UNIVERSITY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200199087-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ROWAN UNIVERSITY | 2020-06-25 | — | — | US | disclosed |
| EP-3625200-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | Rowan University (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213236-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ROWAN UNIVERSITY (US) | 2018-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008297-B2 | Bio-based, multi-aromatic compounds, and methods of making and using same | ALKBH3, ALKBH1, EWSR1 | PDE4A 3930/4885PDE4B 3577/4885PDE4C 3634/4885 |
| US-20200199087-A1 | BIO-BASED, MULTI-AROMATIC COMPOUNDS, AND METHODS OF MAKING AND USING SAME | ALKBH3, ALKBH1, EWSR1 | PDE4A 3930/4885PDE4B 3577/4885PDE4C 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.