Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.58 |
| ▸ | PNP | P00491 | 4/20 | 0.57 |
| ▸ | TK1 | P04183 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986800 | 0.82 | XDH (0.60) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL41787 | 0.81 | XDH (0.59) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL27667185 | 0.81 | XDH (0.63) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL15005119 | 0.81 | XDH (0.59) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL10835122 | 0.79 | XDH (0.61) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL8886034 | 0.79 | XDH (0.58) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL2983847 | 0.79 | XDH (0.57) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL22533906 | 0.79 | XDH (0.57) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL2051364 | 0.79 | XDH (0.57) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL1843776 | 0.79 | XDH (0.57) | XDHPNPTK1BLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630867-B2 | Devices for CRISPR effector system based diagnostics | THE BROAD INSTITUTE, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20250243471-A1 | PROGRAMMABLE PATTERN RECOGNITION COMPOSITIONS | BROAD INST INC (US) | 2025-07-31 | — | — | US | disclosed |
| US-20250223580-A1 | PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS | THE BROAD INSTITUTE, INC. | 2025-07-10 | — | — | US | disclosed |
| US-20250129355-A1 | PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH | 2025-04-24 | — | — | US | disclosed |
| US-20250075268-A1 | CRISPR EFFECTOR SYSTEM BASED DIAGNOSTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2025-03-06 | — | — | US | disclosed |
| US-12203145-B2 | CRISPR effector system based diagnostics for virus detection | THE BROAD INSTITUTE, INC. (US) | 2025-01-21 | — | — | US | disclosed |
| EP-4119663-B1 | CRISPR EFFECTOR SYSTEM BASED DIAGNOSTICS | BROAD INST INC (US) | 2024-11-27 | — | — | EP | disclosed |
| CN-111448311-B | Diagnostic system based on multiple effector CRISPR | 博德研究所 | 2024-11-19 | — | — | CN | disclosed |
| CN-111108220-B | Diagnostic based on CRISPR effect system for virus detection | 博德研究所 | 2024-11-19 | — | — | CN | disclosed |
| US-20240352454-A1 | MULTI-EFFECTOR CRISPR BASED DIAGNOSTIC SYSTEMS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-10-24 | — | — | US | disclosed |
| US-20040127454-A1 | Use of 5-substituted nucleosides and/or prodrugs thereof in the resistance-free treatment of infectious diseases | RESPROTECT GMBH (DE) | 2004-07-01 | — | — | US | disclosed |
| WO-2004029064-A1 | (+)-TRANS-ISOMERS OF (1-PHOSPHONOMETHOXY-2-ALKYLCYCLOPROPYL) METHYL NUCLEOSIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF STEREOISOMERS THEREOF, AND USE OF ANTIVIRAL AGENTS THEREOF | LG LIFE SCIENCES LTD. (KR) | 2004-04-08 | — | — | WO | disclosed |
| EP-1334109-A2 | IMPROVED SYNTHESIS OF PURINE LOCKED NUCLEIC ACID ANALOGUES | Santaris Pharma A/S (DK) | 2003-08-13 | — | — | EP | disclosed |
| US-20020086998-A1 | Synthesis of purine locked nucleic acid analogues | SANTARIS PHARMA A/S (DK) | 2002-07-04 | — | — | US | disclosed |
| WO-2002028875-A2 | IMPROVED SYNTHESIS OF PURINE LOCKED NUCLEIC ACID ANALOGUES | CUREON A/S (DK) | 2002-04-11 | — | — | WO | disclosed |
| WO-2002024323-A2 | HIGH DENSITY MOLECULAR ARRAYS ON POROUS SURFACES | PICOLITER INC. (US) | 2002-03-28 | — | — | WO | disclosed |
| EP-0824536-B1 | ANTIMALARIAL ORGANOMETALLIC IRON COMPLEXES | UNIV LILLE SCIENCES TECH (FR) | 2001-08-22 | — | — | EP | disclosed |
| US-5639440-A | ADMINISTERING MIXTURE OF POLYPEPTIDE AND IMMUNOGEN TO TRANSGENIC MAMMAL HAVING TOLERANCE FOR POLYPEPTIDE YIELDS ANTIBODY CAPABLE OF BINDING IMMUNOGEN | MARTIN JR DAVID W (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0338168-A1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-10-25 | — | — | EP | disclosed |
| US-4508898-A | Antiviral triazine compounds | SYNTEX (U.S.A.) INC. | 1985-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086998-A1 | Synthesis of purine locked nucleic acid analogues | RNGTT, PNP, UNG | XDH 598/4885PNP 2/4885TK1 246/4885 |
| US-20040127454-A1 | Use of 5-substituted nucleosides and/or prodrugs thereof in the resistance-free treatment of infectious diseases | PNP, TYMP, ENTPD5 | XDH 219/4885PNP 1/4885TK1 24/4885 |
| US-12630867-B2 | Devices for CRISPR effector system based diagnostics | ZFR, MTREX, ADAR | XDH 2266/4885PNP 2592/4885TK1 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.