SCHEMBL645784

SCHEMBL645784

Cc1cccc(C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
MYC P01106 1/20 0.37
ROCK2 O75116 1/20 0.35
SIGMAR1 Q99720 3/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
BCHE P06276 1/20 0.33
HTR7 P34969 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
S1PR1 P21453 1/20 0.32
S1PR5 Q9H228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29584884 0.89 SIGMAR1 (0.35) DDB1CRBNMYCROCK2SIGMAR1
SCHEMBL3929841 0.89 SIGMAR1 (0.35) DDB1CRBNMYCROCK2SIGMAR1
SCHEMBL19058034 0.88 ROCK2 (0.34) ROCK2NPC1RAB9APDK2
SCHEMBL1908844 0.87 HPGD (0.36) DDB1CRBNHTR7NPC1RAB9A
SCHEMBL15396855 0.87 ROCK2 (0.43) DDB1CRBNROCK2LMNA
SCHEMBL14117087 0.87 LMNA (0.37) DDB1CRBNROCK2HTR7LMNA
SCHEMBL29391022 0.87 S1PR1 (0.36) DDB1CRBNROCK2SIGMAR1GRIN2D
SCHEMBL197441 0.87 S1PR1 (0.36) DDB1CRBNROCK2SIGMAR1GRIN2D
SCHEMBL29350531 0.87 S1PR1 (0.36) DDB1CRBNROCK2SIGMAR1GRIN2D
SCHEMBL205843 0.86 ROCK2 (0.38) ROCK2SIGMAR1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139838-B1 A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID GRINDEKS JSC (LV) 2012-03-28 EP claimed
EP-2139839-B1 A METHOD FOR PREPARATION OF 6-Ý3-(1-ADAMANTYL)-4-METHOXYPHENYL¨-2-NAPHTOIC ACID GRINDEKS JSC (LV) 2012-03-28 EP claimed
US-8119835-B2 Method for preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoic acid JSC GRINDEKS (LV) 2012-02-21 US claimed
US-20100160677-A1 PROCESS FOR PREPARATION OF 6-[3-(1-ADMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID. JSC GRINDEKS (LV) 2010-06-24 US claimed
US-20100076219-A1 METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID JSC GRINDEKS (LV) 2010-03-25 US claimed
EP-2139838-A2 A PROCESS FOR THE PREPARATION OF 6-Ý3-(1-ADAMANTYL)-4-METHOXYPHENYL-2-NAPHTOIC ACID Grindeks, a joint stock company (LV) 2010-01-06 EP claimed
EP-2139839-A2 A METHOD FOR PREPARATION OF 6-Ý3-(1-ADAMANTYL)-4-METHOXYPHENYL¨-2-NAPHTOIC ACID Grindeks, a joint stock company (LV) 2010-01-06 EP claimed
WO-2008086942-A2 A METHOD FOR PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID KALVINSH IVARS (LV) 2008-07-24 WO claimed
WO-2008080992-A2 A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL-2-NAPHTOIC ACID KALVINSH IVARS (LV) 2008-07-10 WO claimed
US-20230192589-A1 METHOD FOR PRODUCING ESTER COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-06-22 US disclosed
CN-115960051-A Preparation method of stable isotope labeled pyrimethanil internal standard reagent 谱同生物医药科技(常州)有限公司 2023-04-14 CN disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 US disclosed
WO-2008086942-A2 A METHOD FOR PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID KALVINSH IVARS (LV) 2008-07-24 WO disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 US disclosed
US-6951935-B2 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-10-04 US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 US disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG DDB1 1292/4885CRBN 128/4885MYC 204/4885
US-20100076219-A1 METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID HPD, DERA, DHCR7 DDB1 330/4885CRBN 656/4885MYC 1626/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC DDB1 620/4885CRBN 1416/4885MYC 221/4885
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD DDB1 1372/4885CRBN 1261/4885MYC 1574/4885
US-20230192589-A1 METHOD FOR PRODUCING ESTER COMPOUND ADH1A, ACADM, ADH5 DDB1 4859/4885CRBN 2456/4885MYC 711/4885
US-20100160677-A1 PROCESS FOR PREPARATION OF 6-[3-(1-ADMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID. ME1, CD274, PDCD1LG2 DDB1 768/4885CRBN 2960/4885MYC 2806/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS DDB1 1516/4885CRBN 678/4885MYC 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.