Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | APEX1 | P27695 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630933 | 0.86 | POLH (0.89) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630991 | 0.85 | POLH (0.77) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL25865725 | 0.85 | MEN1 (0.59) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL24497194 | 0.83 | POLH (0.72) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL10728956 | 0.83 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL25304942 | 0.81 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL17620378 | 0.81 | POLH (0.89) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL30663836 | 0.81 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630949 | 0.80 | POLH (0.68) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL25262255 | 0.80 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372499-A1 | DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY | THE JOHNS HOPKINS UNIVERSITY | 2023-11-23 | — | — | US | disclosed |
| US-20230233696-A1 | TRIANTENNARY N-ACETYLGALACTOSAMINE MODIFIED HYDROXYL POLYAMIDOAMINE DENDRIMERS AND METHODS OF USE THEREOF | Ashvattha Therapeutics, Inc. (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372499-A1 | DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY | TIE1, FLT3, FLT1 | POLH 838/4885MEN1 651/4885KMT2A 247/4885 |
| US-20230233696-A1 | TRIANTENNARY N-ACETYLGALACTOSAMINE MODIFIED HYDROXYL POLYAMIDOAMINE DENDRIMERS AND METHODS OF USE THEREOF | FUT6, FUT5, OGT | POLH 3085/4885MEN1 3004/4885KMT2A 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.