Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668405 | 0.82 | CA2 (0.50) | ALDH1A1NPSR1CA1CA2CA9 | |
| SCHEMBL20401438 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1CA1CA2 | |
| SCHEMBL20656519 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TDP1CA1CA2 | |
| SCHEMBL31018073 | 0.79 | ALDH1A1 (0.56) | ALDH1A1NPSR1HSD17B10TDP1CA1 | |
| SCHEMBL958949 | 0.79 | ALDH1A1 (0.56) | ALDH1A1NPSR1HSD17B10TDP1CA1 | |
| SCHEMBL1156197 | 0.76 | ALDH1A1 (0.41) | ALDH1A1NPSR1HSD17B10TDP1MAPT | |
| SCHEMBL21773307 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPSR1HSD17B10TDP1CA1 | |
| SCHEMBL30456616 | 0.76 | ALDH1A1 (0.41) | ALDH1A1NPSR1HSD17B10TDP1MAPT | |
| SCHEMBL516599 | 0.76 | ALDH1A1 (0.57) | ALDH1A1NPSR1MAPTGAALMNA | |
| SCHEMBL1278519 | 0.76 | PIK3CD (0.44) | ALDH1A1NPSR1HSD17B10TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745910-B | Chemical compound | 安塔比奥公司 | 2025-05-27 | — | — | CN | disclosed |
| US-20250115576-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12209075-B2 | Pyridine-sulfonamide derivatives as sodium channel inhibitors | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| EP-3655405-B1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2023-06-07 | — | — | EP | disclosed |
| EP-3655405-B1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2023-06-07 | — | — | EP | disclosed |
| CN-115745910-A | Chemical compound | 安塔比奥公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-110446708-B | Chemical compound | 安塔比奥公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20220315546-A1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2022-10-06 | — | — | US | disclosed |
| US-11299467-B2 | Chemical compounds | ANTABIO SAS (FR) | 2022-04-12 | — | — | US | disclosed |
| US-20210214336-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210214336-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2021-07-15 | — | — | US | disclosed |
| EP-3797101-A1 | PYRIDIDNE-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2021-03-31 | — | — | EP | disclosed |
| CN-112368274-A | Pyridine-sulfonamide derivatives as sodium channel inhibitors | 豪夫迈·罗氏有限公司 | 2021-02-12 | — | — | CN | disclosed |
| US-20200339526-A1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2020-10-29 | — | — | US | disclosed |
| US-20200339526-A1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2020-10-29 | — | — | US | disclosed |
| EP-3655405-A1 | CHEMICAL COMPOUNDS | Antabio SAS (FR) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019016393-A1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2019-01-24 | — | — | WO | disclosed |
| EP-3431474-A1 | CHEMICAL COMPOUNDS | Antabio SAS (FR) | 2019-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315546-A1 | CHEMICAL COMPOUNDS | MRPL21, MLX, TXN | ALDH1A1 1565/4885NPSR1 498/4885HSD17B10 3379/4885 |
| US-11299467-B2 | Chemical compounds | MRPL21, MLX, CFTR | ALDH1A1 1225/4885NPSR1 486/4885HSD17B10 3240/4885 |
| US-20200339526-A1 | CHEMICAL COMPOUNDS | MRPL21, MLX, CFTR | ALDH1A1 1225/4885NPSR1 486/4885HSD17B10 3240/4885 |
| US-12209075-B2 | Pyridine-sulfonamide derivatives as sodium channel inhibitors | SCN1B, CACNA1A, SCN1A | ALDH1A1 3192/4885NPSR1 151/4885HSD17B10 4306/4885 |
| US-20210214336-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | SCN1B, CACNA1A, SCN1A | ALDH1A1 3086/4885NPSR1 158/4885HSD17B10 4292/4885 |
| US-20250115576-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | F12, REN, ZYX | ALDH1A1 2171/4885NPSR1 125/4885HSD17B10 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.