SCHEMBL20656646

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22304387	0.92	CA2 (0.50)	CA2CA1MAPK1ALDH1A1PDF
	SCHEMBL2058687	0.90	CA2 (0.68)	CA2CA1MAPK1USP2ALDH1A1
	SCHEMBL25732354	0.89	CA2 (0.66)	CA2CA1MAPK1USP2ALDH1A1
	SCHEMBL12873393	0.84	PDF (0.57)	CA2CA1PDF
	SCHEMBL11095965	0.81	CA2 (0.66)	CA2CA1MAPK1USP2ALDH1A1
	SCHEMBL9652484	0.81	CA2 (0.56)	CA2CA1MAPK1USP2ALDH1A1
	SCHEMBL21340001	0.80	HDAC8 (0.56)	CA2CA1SMN1; SMN2LMNATSHR
	SCHEMBL24124963	0.79	CA2 (0.53)	CA2CA1MAPK1USP2PDF
	SCHEMBL16389960	0.79	CA2 (0.63)	CA2CA1MAPK1USP2ALDH1A1
	SCHEMBL2058865	0.79	CA2 (0.63)	CA2CA1MAPK1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.