Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634946 | 0.86 | ITGB3 (0.55) | ALOX5MAOBFFAR1LTA4HITGB3 | |
| SCHEMBL6474783 | 0.86 | ITGB3 (0.55) | ALOX5MAOBFFAR1LTA4HITGB3 | |
| SCHEMBL29397771 | 0.86 | ITGB3 (0.55) | ALOX5MAOBFFAR1LTA4HITGB3 | |
| SCHEMBL20693063 | 0.85 | ALOX5 (0.42) | ALOX5MAOBLTB4RLTB4R2FFAR1 | |
| SCHEMBL18918265 | 0.84 | LTA4H (0.52) | ALOX5MAOBLTB4RLTB4R2FFAR1 | |
| SCHEMBL20693061 | 0.84 | MAOB (0.48) | ALOX5MAOBFFAR1LTA4HITGB3 | |
| SCHEMBL6942693 | 0.80 | LDHA (0.54) | L3MBTL1ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL3776724 | 0.80 | LDHA (0.54) | L3MBTL1ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL24443461 | 0.80 | MAPT (0.49) | L3MBTL1NPC1POLBRAB9APPARG | |
| SCHEMBL6890932 | 0.79 | PSMB1 (0.49) | MAOBLTB4RLTB4R2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019018890-A1 | NOVEL SPIROCYCLIC COMPOUNDS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2019-01-31 | — | — | WO | disclosed |