Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26005245 | 0.85 | ROCK2 (0.43) | ROCK2ROCK1NOS1AURKAAURKB | |
| SCHEMBL23135393 | 0.84 | AURKA (0.40) | NOS1AURKAMAPTPKMALDH1A1 | |
| SCHEMBL16181566 | 0.83 | NOS1 (0.54) | NOS1MAPTPKMALDH1A1LMNA | |
| SCHEMBL23135375 | 0.81 | IDO1 (0.40) | MAPTLMNAPTPN1PRSS1F7 | |
| SCHEMBL10648740 | 0.79 | TAAR1 (0.56) | AURKAALDH1A1LMNAF10 | |
| SCHEMBL23135392 | 0.79 | ADRA2A (0.41) | NOS1ALDH1A1PTPN1PRSS1F7 | |
| SCHEMBL694147 | 0.78 | CYP1A2 (0.54) | ROCK2ROCK1MAPTPKMALDH1A1 | |
| SCHEMBL2717977 | 0.77 | PRSS1 (0.55) | NOS1MAPTPKMALDH1A1LMNA | |
| SCHEMBL14470339 | 0.77 | ALDH1A1 (0.46) | NOS1MAPTPKMALDH1A1LMNA | |
| SCHEMBL17701355 | 0.77 | PKM (0.61) | ROCK2ROCK1AURKAAURKBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230264171-A1 | CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND | BIO-RAD LABORATORIES, INC. | 2023-08-24 | — | — | US | disclosed |
| US-20230264171-A1 | CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND | BIO-RAD LABORATORIES, INC. | 2023-08-24 | — | — | US | disclosed |
| US-11666888-B2 | Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand | BIO-RAD LABORATORIES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| WO-2019027366-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11666888-B2 | Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand | MSR1, RXRA, MLX | ROCK2 2973/4885ROCK1 3063/4885NOS1 4422/4885 |
| US-20230264171-A1 | CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND | MSR1, RXRA, MLX | ROCK2 2973/4885ROCK1 3063/4885NOS1 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.