Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20745005 | 1.00 | MMP8 (0.59) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL25046046 | 0.88 | MMP8 (0.49) | MMP8ALDH1A1RECQLHPGDMAPT | |
| SCHEMBL8710582 | 0.81 | MMP8 (0.79) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL20744888 | 0.80 | HPGD (0.42) | MMP8ALDH1A1RECQLTAAR1HPGD | |
| SCHEMBL20744890 | 0.80 | HPGD (0.42) | MMP8ALDH1A1RECQLTAAR1HPGD | |
| SCHEMBL9526598 | 0.80 | MMP8 (0.73) | MMP8ALDH1A1RECQLPIN1TAAR1 | |
| SCHEMBL20744889 | 0.79 | HPGD (0.39) | MMP8ALDH1A1RECQLTAAR1HPGD | |
| SCHEMBL20744891 | 0.79 | HPGD (0.39) | MMP8ALDH1A1RECQLTAAR1HPGD | |
| SCHEMBL28399342 | 0.78 | TRPA1 (0.38) | MMP8ALDH1A1RECQLHPGDPAM | |
| SCHEMBL20745009 | 0.75 | PKM (0.34) | MMP8ALDH1A1RECQLPIN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875822-B2 | Directed β-C(sp3)#H iodination and arylation of ketones | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-29 | — | — | US | disclosed |
| US-10875822-B2 | Directed β-C(sp3)#H iodination and arylation of ketones | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | THE SCRIPPS RESEARCH INSTITUTE | 2020-08-13 | — | — | US | disclosed |
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | THE SCRIPPS RESEARCH INSTITUTE | 2020-08-13 | — | — | US | disclosed |
| WO-2019036349-A1 | DIRECTED B-C(SP3)-H IODINATION AND ARYLATION OF KETONES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019036349-A1 | DIRECTED B-C(SP3)-H IODINATION AND ARYLATION OF KETONES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | BCAT1, AOC3, SPIN3 | MMP8 3894/4885ALDH1A1 1244/4885RECQL 4875/4885 |
| US-10875822-B2 | Directed β-C(sp3)#H iodination and arylation of ketones | BCAT1, AOC3, SPIN3 | MMP8 3775/4885ALDH1A1 1290/4885RECQL 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.