Tribromoacetic Acid

Tribromoacetic Acid

SCHEMBL2076262

O=C([O-])C(Br)(Br)Br.[Na+]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Tribromoacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118431475-A Carbon-based positive electrode material, preparation method thereof and double-ion battery 中国科学院深圳先进技术研究院 2024-08-02 CN claimed
CN-111004130-B Method for purifying 1,2-propane diamine 西安近代化学研究所 2023-03-21 CN claimed
CN-111004130-A Method for purifying 1, 2-propane diamine 西安近代化学研究所 2020-04-14 CN claimed
US-8927739-B2 Processes for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives ENANTA PHARMACEUTICALS, INC. (US) 2015-01-06 US claimed
US-20140187793-A1 PROCESSES FOR THE PREPARATION OF 5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID AND ITS DERIVATIVES ENANTA PHARMACEUTICALS, INC. (US) 2014-07-03 US claimed
EP-2709455-A2 PROCESSES FOR THE PREPARATION OF 5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID AND ITS DERIVATIVES Enanta Pharmaceuticals, Inc. (US) 2014-03-26 EP claimed
WO-2012158861-A2 PROCESSES FOR THE PREPARATION OF 5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID AND ITS DERIVATIVES ENANTA PHARMACEUTICALS, INC. (US) 2012-11-22 WO claimed
US-20090012303-A1 CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES AEROJET FINE CHEMICALS LLC (US) 2009-01-08 US claimed
US-6867311-B2 Clean, high-yield preparation of S,S and R,S amino acid isosteres AEROJET FINE CHEMICALS LLC (US) 2005-03-15 US claimed
US-20030225292-A1 Clean, high-yield preparation of S,S and R,S amino acid isosteres AEROJET FINE CHEMICALS LLC, A DELAWARE LIMITED LIABILITY COMPANY 2003-12-04 US claimed
EP-0444240-B1 A method for classifying leukocytes and a reagent used therefor TOA MEDICAL ELECTRONICS (JP) 1996-06-26 EP claimed
EP-0316453-B1 METHOD FOR CLASSIFYING LEUKOCYTES AND REAGENTS TOA MEDICAL ELECTRONICS (JP) 1996-03-27 EP claimed
US-5389549-A Method for classifying leukocytes and a reagent used therefor TOA MEDICAL ELECTRONICS CO., LTD. (JP) 1995-02-14 US claimed
WO-1992018649-A1 COMPOSITIONS AND METHODS FOR IMPROVED EXTRACTION AND HYBRIDIZATION OF NUCLEIC ACID MICROPROBE CORPORATION (US) 1992-10-29 WO claimed
EP-0444240-A1 A method for classifying leukocytes and a reagent used therefor TOA MEDICAL ELECTRONICS CO., LTD. (JP) 1991-09-04 EP claimed
CN-118431475-A Carbon-based positive electrode material, preparation method thereof and double-ion battery 中国科学院深圳先进技术研究院 2024-08-02 CN disclosed
CN-111004130-B Method for purifying 1,2-propane diamine 西安近代化学研究所 2023-03-21 CN disclosed
US-4285882-A CHEMICAL INTERMEDIATES FOR INSECTICIDES SHELL OIL COMPANY (US) 1981-08-25 US disclosed
EP-0016504-A2 Novel trihaloethyl carbonate derivatives and a process for their production SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-10-01 EP disclosed
US-4167528-A Process for the production of tetrabromoethylene MONSANTO COMPANY (US) 1979-09-11 US disclosed