Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378902 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL16372579 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL25566397 | 0.75 | F10 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24131432 | 0.75 | PGR (0.45) | ALDH1A1CYP3A4KMT2ATDP1MAPT | |
| SCHEMBL4126225 | 0.75 | KDM4E (0.39) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2079427 | 0.75 | ALDH1A1 (0.42) | ALDH1A1CYP3A4SMN1; SMN2FFAR4ADRA1A | |
| SCHEMBL29961263 | 0.74 | FFAR4 (0.56) | ALDH1A1CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL77088 | 0.74 | FFAR4 (0.56) | ALDH1A1CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL5958670 | 0.71 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL3576845 | 0.71 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856070-B1 | NOVEL DRUGS FOR TREATING RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-20110053926-A1 | New Pharmaceutically-Active Compounds for the Treatment of Respiratory Diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20100233268-A1 | POWDER FORMULATIONS FOR INHALATION CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-7709474-B2 | Enantiomerically pure beta agonists, manufacturing and use thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-2094271-A2 | DRUG COMBINATIONS FOR TREATING AIRWAY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2009-09-02 | — | — | EP | disclosed |
| EP-2056836-A1 | POWDER FORMULATIONS FOR INHALATION CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS | Boehringer Ingelheim International GmbH (DE) | 2009-05-13 | — | — | EP | disclosed |
| EP-2057134-A1 | SINGLE ENANTIOMER BETA AGONISTS METHOD FOR PRODUCTION AND USE THEREOF AS A MEDICAMENT | Boehringer Ingelheim International GmbH (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-20090105236-A1 | NEW PHARMACEUTICALLY-ACTIVE COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20080070909-A1 | ENANTIOMERICALLY PURE BETA AGONISTS, MANUFACTURING AND USE THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| WO-2008023001-A1 | POWDER FORMULATIONS FOR INHALATION CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023003-A1 | DRUG COMBINATIONS FOR TREATING AIRWAY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023004-A1 | SINGLE ENANTIOMER BETA AGONISTS METHOD FOR PRODUCTION AND USE THEREOF AS A MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |
| US-20080051392-A1 | PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF RESPIRATORY DISEASES | KONETZKI INGO | 2008-02-28 | — | — | US | disclosed |
| EP-1856070-A1 | NOVEL DRUGS FOR TREATING RESPIRATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006089859-A1 | NOVEL DRUGS FOR TREATING RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-08-31 | — | — | WO | disclosed |
| US-20060189605-A1 | NEW PHARMACEUTICALLY-ACTIVE COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105236-A1 | NEW PHARMACEUTICALLY-ACTIVE COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | CFTR, SDHA, HRH1 | ALDH1A1 767/4885CYP3A4 338/4885MEN1 1840/4885 |
| US-20100233268-A1 | POWDER FORMULATIONS FOR INHALATION CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS | ADRB2, ADRB3, ADRB1 | ALDH1A1 857/4885CYP3A4 509/4885MEN1 2250/4885 |
| US-20060189605-A1 | NEW PHARMACEUTICALLY-ACTIVE COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | CFTR, SDHA, HRH1 | ALDH1A1 767/4885CYP3A4 338/4885MEN1 1840/4885 |
| US-20080070909-A1 | ENANTIOMERICALLY PURE BETA AGONISTS, MANUFACTURING AND USE THEREOF | ADRB1, ADRB2, ADRB3 | ALDH1A1 1529/4885CYP3A4 239/4885MEN1 1153/4885 |
| US-20110053926-A1 | New Pharmaceutically-Active Compounds for the Treatment of Respiratory Diseases | CFTR, SDHA, HRH1 | ALDH1A1 767/4885CYP3A4 338/4885MEN1 1840/4885 |
| US-20080051392-A1 | PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF RESPIRATORY DISEASES | CHRM2, CFTR, TPSB2 | ALDH1A1 657/4885CYP3A4 363/4885MEN1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.