Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207168 | 0.83 | ALDH1A1 (0.44) | F7F3DYRK1AAHRNOS1 | |
| SCHEMBL28796612 | 0.81 | JAK2 (0.48) | BACE1 | |
| SCHEMBL208893 | 0.75 | KDM4E (0.36) | AHRALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL5981619 | 0.75 | DYRK1A (0.42) | DYRK1AALDH1A1HPGDPOLBHTR3A | |
| SCHEMBL206867 | 0.75 | NOS1 (0.38) | DYRK1AAHRNR4A2NOS1ALDH1A1 | |
| SCHEMBL7221951 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HPGDPOLBALOX15KDM4E | |
| SCHEMBL7186585 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL440275 | 0.74 | MAPK13 (0.41) | DYRK1AALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27864312 | 0.73 | MAP4K4 (0.44) | BACE1 | |
| SCHEMBL208230 | 0.73 | LMNA (0.42) | F7F3DYRK1AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201911-A | Compounds and their use as GPR183 inhibitors | 南京艾美斐生物医药科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116438160-A | Carbamoyl compounds for the treatment of viral infections | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | claimed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | claimed |
| EP-3386973-B1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-12 | — | — | EP | claimed |
| EP-2809668-B1 | 4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-04-12 | — | — | EP | claimed |
| US-9266876-B2 | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-02-23 | — | — | US | claimed |
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | claimed |
| US-20140371204-A1 | 4-(Benzoimidazol-2-yl)-thiazole Compounds and Related Aza Derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2014-12-18 | — | — | US | claimed |
| EP-2809668-A1 | 4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2014-12-10 | — | — | EP | claimed |
| US-8697685-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2014-04-15 | — | — | US | claimed |
| WO-2004018431-A2 | NOVEL PHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | claimed |
| EP-1392639-A1 | PYRUVATE DERIVATIVES | Galileo Laboratories, Inc. (US) | 2004-03-03 | — | — | EP | claimed |
| US-20030203897-A1 | 2,4-Disubstituted thiazolyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-10-30 | — | — | US | claimed |
| US-20030013847-A1 | Cytoprotective agents | MONSANTO TECHNOLOGY LLC | 2003-01-16 | — | — | US | claimed |
| EP-1261607-A1 | 2,4-DISUBSTITUTED THIAZOLYL DERIVATIVES | Janssen Pharmaceutica N.V. (BE) | 2002-12-04 | — | — | EP | claimed |
| WO-2002090314-A1 | PYRUVATE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2002-11-14 | — | — | WO | claimed |
| WO-2001064674-A1 | 2,4-DISUBSTITUTED THIAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-09-07 | — | — | WO | claimed |
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | claimed |
| CN-1225013-A | Non-peptide G-CSF mimetics | SMITHKLINE BEECHAM CORP (US) | 1999-08-04 | — | — | CN | claimed |
| EP-0335646-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013847-A1 | Cytoprotective agents | PC, PDK1, PDK2 | F7 4236/4885F3 810/4885DYRK1A 1197/4885 |
| US-20030203897-A1 | 2,4-Disubstituted thiazolyl derivatives | IL4, PTGER4, PTGER1 | F7 2582/4885F3 1049/4885DYRK1A 3232/4885 |
| US-20140371204-A1 | 4-(Benzoimidazol-2-yl)-thiazole Compounds and Related Aza Derivatives | CXCR3, CXCR1, CXCR2 | F7 3884/4885F3 1461/4885DYRK1A 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.