Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768303 | 0.89 | MMP2 (0.37) | KDM1ASLC6A9 | |
| SCHEMBL20768325 | 0.89 | MMP2 (0.37) | KDM1ASLC6A9 | |
| SCHEMBL20786605 | 0.88 | CTSS (0.35) | — | |
| SCHEMBL20786667 | 0.88 | CTSS (0.35) | — | |
| SCHEMBL20768327 | 0.84 | CTSL (0.44) | — | |
| SCHEMBL20768326 | 0.81 | KDM4E (0.36) | — | |
| SCHEMBL3060635 | 0.79 | CTSS (0.45) | — | |
| SCHEMBL20768312 | 0.79 | MMP2 (0.36) | — | |
| SCHEMBL20768315 | 0.79 | MMP2 (0.36) | — | |
| SCHEMBL28452123 | 0.78 | SLC6A9 (0.30) | KDM1ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574422-B | Phenyl difluoromethyl substituted prolinamide compounds | 安斯泰来制药株式会社 | 2023-09-08 | — | — | CN | disclosed |
| CN-111574422-A | Phenyl difluoromethyl substituted prolyl compounds | 安斯泰来制药株式会社 | 2020-08-25 | — | — | CN | disclosed |
| CN-110248925-B | Phenyl difluoromethyl substituted prolyl compounds | 安斯泰来制药株式会社 | 2020-07-17 | — | — | CN | disclosed |
| US-20190248738-A1 | PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-20190248738-A1 | PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-10322997-B2 | Phenyldifluoromethyl-substituted prolinamide compound | ASTELLAS PHARMA INC. (JP) | 2019-06-18 | — | — | US | disclosed |
| US-10322997-B2 | Phenyldifluoromethyl-substituted prolinamide compound | ASTELLAS PHARMA INC. (JP) | 2019-06-18 | — | — | US | disclosed |
| US-20190071398-A1 | PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2019-03-07 | — | — | US | disclosed |
| US-20190071398-A1 | PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248738-A1 | PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND | CTSV, CTSS, CTSF | KDM1A 205/4885SLC6A9 1632/4885 |
| US-10322997-B2 | Phenyldifluoromethyl-substituted prolinamide compound | CTSV, CTSS, CTSF | KDM1A 205/4885SLC6A9 1632/4885 |
| US-20190071398-A1 | PHENYLDIFLUOROMETHYL-SUBSTITUTED PROLINAMIDE COMPOUND | CTSS, CTSV, CTSF | KDM1A 999/4885SLC6A9 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.