Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20769685 | 0.84 | ALDH1A1 (0.60) | TBXAS1ALDH1A1LMNAICMTPPARD | |
| SCHEMBL20769736 | 0.81 | ALDH1A1 (0.60) | TBXAS1ALDH1A1LMNAICMTPPARD | |
| SCHEMBL20769672 | 0.81 | AKR1C3 (0.56) | TBXAS1ALDH1A1LMNAICMTPPARD | |
| SCHEMBL20787937 | 0.81 | LOXL2 (0.37) | TBXAS1ICMTKDM4CCHRM1 | |
| SCHEMBL20769719 | 0.79 | ALDH1A1 (0.65) | TBXAS1ALDH1A1LMNAICMTPPARD | |
| SCHEMBL20769663 | 0.78 | ALDH1A1 (0.56) | TBXAS1ALDH1A1LMNAICMTPPARD | |
| SCHEMBL20769700 | 0.78 | LMNA (0.75) | ALDH1A1LMNAICMTPPARDPPARG | |
| SCHEMBL20769651 | 0.77 | ALDH1A1 (0.60) | TBXAS1ALDH1A1LMNAICMTPPARD | |
| SCHEMBL20769686 | 0.77 | SLC22A12 (0.59) | ALDH1A1LMNAICMTPPARDAKR1C3 | |
| SCHEMBL20769743 | 0.75 | LMNA (0.82) | ALDH1A1LMNAICMTPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046668-A1 | AMIDE SUBSTITUTED THIAZOLES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-03-07 | — | — | WO | disclosed |