Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | ICMT | O60725 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20769700 | 0.88 | LMNA (0.75) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769685 | 0.87 | ALDH1A1 (0.60) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769743 | 0.85 | LMNA (0.82) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769719 | 0.84 | ALDH1A1 (0.65) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769663 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769698 | 0.81 | TBXAS1 (0.48) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20787975 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769677 | 0.79 | LMNA (0.56) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769653 | 0.79 | ALDH1A1 (0.61) | ALDH1A1LMNAPPARDPPARGPPARA | |
| SCHEMBL20769668 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNAPPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046668-A1 | AMIDE SUBSTITUTED THIAZOLES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-03-07 | — | — | WO | disclosed |