Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772498 | 0.86 | GABRA2 (0.47) | ALDH1A1MAPTHTTIKBKBMEN1 | |
| SCHEMBL20772497 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL20772396 | 0.84 | FKBP1A (0.51) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL20796095 | 0.82 | MAPK1 (0.49) | HSD11B1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL10332010 | 0.73 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPK1HTTMEN1 | |
| SCHEMBL20796243 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL20772762 | 0.72 | KMT2A (0.51) | HSD11B1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL20773212 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL3164037 | 0.72 | RAB9A (0.50) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL11083765 | 0.72 | HPGD (0.58) | ALDH1A1MAPTIKBKBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3676260-B1 | THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) | 2024-10-30 | — | — | EP | claimed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | claimed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | claimed |
| EP-3676260-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | Ahammune Biosciences Private Limited (IN) | 2020-07-08 | — | — | EP | claimed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | claimed |
| EP-3676260-B1 | THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) | 2024-10-30 | — | — | EP | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | disclosed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | disclosed |
| EP-3676260-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | Ahammune Biosciences Private Limited (IN) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | TPMT, TST, SSB | HSD11B1 111/4885ALDH1A1 1352/4885LMNA 4770/4885 |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | TPMT, TST, UACA | HSD11B1 363/4885ALDH1A1 1873/4885LMNA 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.