SCHEMBL20809079

SCHEMBL20809079

Cc1cc(C)cc(-c2ccc3ccc(C4CCCC4)cc3n2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.42
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38
DHODH Q02127 2/20 0.37
PSMB5 P28074 2/20 0.35
HRH3 Q9Y5N1 3/20 0.35
CDK9 P50750 1/20 0.35
DYRK1A Q13627 1/20 0.35
DYRK2 Q92630 1/20 0.35
KCNH2 Q12809 2/20 0.35
HRH4 Q9H3N8 2/20 0.35
IGF1R P08069 2/20 0.35
CYP3A4 P08684 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CASP3 P42574 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
SIGMAR1 Q99720 1/20 0.34
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809059 0.99 BACE1 (0.44) BACE1PDGFRBPDGFRADHODHPSMB5
SCHEMBL20809309 0.90 BACE1 (0.55) BACE1PDGFRBPDGFRADHODHPSMB5
SCHEMBL20809057 0.89 BACE1 (0.57) BACE1PDGFRBPDGFRADHODHPSMB5
SCHEMBL20809303 0.87 CASP3 (0.46) BACE1DHODHCASP3SENP7SENP6
SCHEMBL20809060 0.86 CASP3 (0.48) BACE1DHODHNPC1RAB9ACASP3
SCHEMBL20809297 0.82 DHODH (0.50) BACE1DHODHIGF1RCYP3A4NPC1
SCHEMBL24596719 0.82 NPC1 (0.45) BACE1DHODHCYP3A4NPC1RAB9A
SCHEMBL20809058 0.81 DHODH (0.52) BACE1DHODHHRH3IGF1RCYP3A4
SCHEMBL20809307 0.78 BACE1 (0.51) BACE1DHODHPSMB5HRH3NPC1
SCHEMBL24756262 0.77 ABL1 (0.42) BACE1PDGFRBPDGFRAPSMB5HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 BACE1 3381/4885PDGFRB 1657/4885PDGFRA 1089/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 BACE1 3381/4885PDGFRB 1657/4885PDGFRA 1089/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB BACE1 2308/4885PDGFRB 4822/4885PDGFRA 4841/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 BACE1 3964/4885PDGFRB 1507/4885PDGFRA 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.