SCHEMBL20809400

SCHEMBL20809400

Cc1cc(C)cc(-c2ncnc3c2sc2ccccc23)c1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 7/20 0.54
▸ CDK5 Q00535 1/20 0.54
▸ CDK5R1 Q15078 1/20 0.54
▸ HRH4 Q9H3N8 1/20 0.50
▸ EGFR P00533 5/20 0.47
▸ HTR2C P28335 1/20 0.47
▸ PIK3CA P42336 1/20 0.46
▸ TP53 P04637 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ TNKS O95271 1/20 0.40
▸ TNKS2 Q9H2K2 1/20 0.40
▸ MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17754619 0.89 LIMK1 (0.51) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL24796187 0.89 LIMK1 (0.46) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL17754623 0.87 LIMK1 (0.55) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL24796206 0.86 LIMK1 (0.47) LIMK1EGFR
SCHEMBL24795196 0.85 HRH4 (0.43) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL16901973 0.83 LIMK1 (0.61) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL26351585 0.81 HTR2C (0.49) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL20809408 0.80 LIMK1 (0.45) LIMK1EGFR
SCHEMBL25841453 0.80 LIMK1 (0.56) LIMK1CDK5CDK5R1HRH4EGFR
SCHEMBL23185176 0.79 LIMK1 (0.52) LIMK1CDK5CDK5R1HRH4EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 — — US disclosed
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 — — US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 — — US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 — — US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 LIMK1 311/4885CDK5 1014/4885CDK5R1 1625/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 LIMK1 311/4885CDK5 1014/4885CDK5R1 1625/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB LIMK1 281/4885CDK5 3246/4885CDK5R1 4096/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 LIMK1 742/4885CDK5 841/4885CDK5R1 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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