Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828341 | 0.89 | DGAT1 (0.48) | ROCK2DGAT1KMT2AMEN1SLC2A1 | |
| SCHEMBL20828420 | 0.88 | DGAT1 (0.47) | ROCK2DGAT1KMT2AMEN1SLC2A1 | |
| SCHEMBL20828418 | 0.82 | DGAT1 (0.44) | ROCK2DGAT1KMT2AMEN1SLC2A1 | |
| SCHEMBL20828421 | 0.78 | SCD (0.43) | ROCK2DGAT1KMT2AMEN1SLC2A1 | |
| SCHEMBL20820817 | 0.78 | DGAT1 (0.50) | ROCK2DGAT1SLC2A1 | |
| SCHEMBL20828481 | 0.78 | FFAR1 (0.45) | ROCK2DGAT1MAPK14RAB9A | |
| SCHEMBL20828403 | 0.77 | DGAT1 (0.41) | ROCK2DGAT1MAPTMAPK1NPC1 | |
| SCHEMBL20828340 | 0.76 | BRAF (0.46) | ROCK2DGAT1MAPK14 | |
| SCHEMBL20828451 | 0.76 | BRAF (0.44) | ROCK2MAPK14SLC2A1RAB9A | |
| SCHEMBL20828342 | 0.76 | DGAT1 (0.58) | DGAT1KMT2AMEN1SLC2A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |