Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846827 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL20848347 | 0.78 | CYP3A4 (0.39) | ALDH1A1DDB1CRBNPOLB | |
| SCHEMBL24885613 | 0.75 | NAAA (0.44) | ALDH1A1MAPK1L3MBTL1LMNAPOLB | |
| SCHEMBL12938624 | 0.74 | NAAA (0.45) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL20848641 | 0.74 | LIPE (0.35) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL21011264 | 0.74 | MEN1 (0.42) | ALDH1A1DDB1CRBNKDM4ELMNA | |
| SCHEMBL18256732 | 0.73 | NAAA (0.41) | ALDH1A1MAPK1LMNAPOLBNPC1 | |
| SCHEMBL847109 | 0.73 | POLB (0.35) | ALDH1A1DDB1CRBNPOLB | |
| SCHEMBL15198823 | 0.73 | NAAA (0.41) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL16417655 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPK1L3MBTL1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190091338-A1 | MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190091338-A1 | MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS | COQ8A, COQ8B, STARD7 | ALDH1A1 4420/4885MAPK1 3428/4885L3MBTL1 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.