Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847441 | 0.78 | TSHR (0.52) | TSHRL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL18531360 | 0.73 | — | — | |
| SCHEMBL19124738 | 0.73 | KMT2A (0.43) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL846827 | 0.73 | ALDH1A1 (0.47) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL10262393 | 0.69 | TSHR (0.44) | TSHRL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL20848347 | 0.69 | CYP3A4 (0.39) | MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL1300684 | 0.68 | TSHR (0.43) | TSHRL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL12938624 | 0.66 | NAAA (0.45) | TSHRL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL15502254 | 0.66 | RAB9A (0.42) | MEN1KMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL258710 | 0.66 | NPC1 (0.34) | TSHRNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190091338-A1 | MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190091338-A1 | MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS | COQ8A, COQ8B, STARD7 | TSHR 4074/4885L3MBTL1 986/4885MEN1 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.