Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262393 | 0.84 | TSHR (0.44) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL28443894 | 0.84 | SMN1; SMN2 (0.51) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL13575063 | 0.80 | ALDH1A1 (0.55) | TSHRKMT2AHPGDLMNAHTT | |
| SCHEMBL20848664 | 0.78 | TSHR (0.39) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL1525284 | 0.77 | SMN1; SMN2 (0.54) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL1300684 | 0.77 | TSHR (0.43) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL19124738 | 0.75 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21077981 | 0.75 | SMN1; SMN2 (0.51) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL16565171 | 0.73 | METAP2 (0.51) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL20150450 | 0.73 | POLB (0.47) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-11180608-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-11149114-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-10-19 | — | — | US | disclosed |
| US-10980234-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2021-04-20 | — | — | US | disclosed |
| US-10779539-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC. (US) | 2020-09-22 | — | — | US | disclosed |
| EP-3259292-B1 | BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) | 2020-04-08 | — | — | EP | disclosed |
| US-10610597-B2 | Polycarbonates bearing aromatic N-heterocycles for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-04-07 | — | — | US | disclosed |
| US-10457759-B2 | Co-delivery of cholesterol lowering drugs and nutraceuticals | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-10-29 | — | — | US | disclosed |
| EP-2516502-B1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | IBM (US) | 2019-05-15 | — | — | EP | disclosed |
| WO-2011078804-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011078803-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110151566-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110151566-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149114-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | DCLRE1A, ODC1, MRTO4 | TSHR 4384/4885MEN1 3087/4885KMT2A 1645/4885 |
| US-11180608-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | DCLRE1A, ODC1, MRTO4 | TSHR 4384/4885MEN1 3087/4885KMT2A 1645/4885 |
| US-10980234-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | TSHR 1864/4885MEN1 2821/4885KMT2A 4588/4885 |
| US-10457759-B2 | Co-delivery of cholesterol lowering drugs and nutraceuticals | STARD3, HMGCR, CETP | TSHR 4338/4885MEN1 4236/4885KMT2A 3617/4885 |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | TSHR 1864/4885MEN1 2821/4885KMT2A 4588/4885 |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | TSHR 4155/4885MEN1 3094/4885KMT2A 3066/4885 |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | TSHR 1728/4885MEN1 2426/4885KMT2A 4165/4885 |
| US-10779539-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | TSHR 1864/4885MEN1 2821/4885KMT2A 4588/4885 |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | SAMM50, ADRM1, UFM1 | TSHR 1975/4885MEN1 3976/4885KMT2A 3339/4885 |
| US-10610597-B2 | Polycarbonates bearing aromatic N-heterocycles for drug delivery | PAH, SULT1E1, SULT1A1 | TSHR 4486/4885MEN1 3599/4885KMT2A 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.