Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20857036 | 0.78 | AVPR1A (0.48) | OPRM1 | |
| SCHEMBL20857048 | 0.78 | OPRM1 (0.56) | OPRM1 | |
| SCHEMBL20857039 | 0.77 | CYP2C9 (0.55) | OPRM1 | |
| SCHEMBL20857066 | 0.76 | HTT (0.50) | OPRM1 | |
| SCHEMBL7472433 | 0.75 | HRH4 (0.56) | RBP4HRH4PDE10A | |
| SCHEMBL22718876 | 0.74 | HRH4 (0.76) | RBP4HRH4PDE10A | |
| SCHEMBL20857072 | 0.73 | MAPT (0.47) | OPRM1 | |
| SCHEMBL23175993 | 0.73 | AGER (0.63) | OPRM1 | |
| SCHEMBL9832108 | 0.73 | HRH4 (0.74) | RBP4HRH4PDE10A | |
| SCHEMBL30358191 | 0.73 | HRH4 (0.74) | RBP4HRH4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3688472-A1 | CONJUGATED PROTEINS AND USES THEREOF | The Scripps Research Institute (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019067741-A1 | CONJUGATED PROTEINS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | KEAP1, GSTK1, GSTM2 | RBP4 738/4885HRH4 3897/4885PDE10A 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.