Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22387777 | 0.93 | RNF4 (0.43) | RNF4ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL23256713 | 0.92 | UBE2M (0.41) | UBE2MDCUN1D1RAF1STAT3CETP | |
| SCHEMBL20857040 | 0.82 | RNF4 (0.48) | RNF4ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL20857037 | 0.81 | RNF4 (0.41) | RNF4ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL22371835 | 0.79 | NPC1 (0.44) | RNF4ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL20857061 | 0.75 | STK39 (0.41) | RNF4ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL22387774 | 0.74 | MAPK10 (0.42) | RNF4ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL22387776 | 0.68 | L3MBTL1 (0.56) | ALDH1A1NPC1HTTRAB9ARAF1 | |
| SCHEMBL21168598 | 0.66 | CYP3A4 (0.46) | L3MBTL1 | |
| SCHEMBL18763021 | 0.66 | GSTO1 (0.48) | CETPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3688472-A1 | CONJUGATED PROTEINS AND USES THEREOF | The Scripps Research Institute (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019067741-A1 | CONJUGATED PROTEINS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | KEAP1, GSTK1, GSTM2 | RNF4 993/4885ALDH1A1 1225/4885NPC1 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.