SCHEMBL20857779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20857791	0.93	GSTP1 (0.39)	CYP1B1CYP1A2GSTP1CYP1A1GPR84
	SCHEMBL20857939	0.86	RET (0.31)	—
	SCHEMBL20857932	0.83	HSD17B10 (0.39)	HSD17B10TDP1MAPTL3MBTL1
	SCHEMBL20858026	0.83	HSD17B10 (0.41)	ALDH1A1HSD17B10TDP1HPGDMAPT
	SCHEMBL25459727	0.81	KDM4E (0.37)	ALDH1A1HSD17B10TDP1HPGDMAPT
	SCHEMBL20857879	0.81	HSD17B10 (0.34)	HSD17B10TDP1MAPT
	SCHEMBL25459725	0.80	KDM4E (0.36)	ALDH1A1HSD17B10HPGDMAPTL3MBTL1
	SCHEMBL21710698	0.80	ALDH1A1 (0.41)	ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
	SCHEMBL20857876	0.79	HSD17B10 (0.35)	HSD17B10L3MBTL1
	SCHEMBL21718333	0.79	HSD17B10 (0.40)	ALDH1A1HSD17B10CYP1B1HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.