Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.62 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | FER | P16591 | 1/20 | 0.55 |
| ▸ | LTK | P29376 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CASP9 | P55211 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087698 | 0.84 | TDP2 (0.66) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9025701 | 0.82 | TDP2 (0.68) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9056394 | 0.82 | NPC1 (0.64) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18020364 | 0.81 | CSNK1G1 (0.56) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL13629274 | 0.80 | CYP1A2 (0.54) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL13629289 | 0.80 | CYP1A2 (0.54) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6469101 | 0.79 | NPC1 (0.72) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL407439 | 0.78 | NPC1 (0.70) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL14084317 | 0.77 | TDP2 (0.61) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL10032 | 0.77 | NPC1 (1.00) | NPC1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021190-B1 | Amid derivatives as growth hormone release promotors | KAKEN PHARMA CO LTD (JP) | 2006-11-08 | — | — | EP | claimed |
| WO-2023141855-A1 | PROTEIN CONJUGATES WITH MULTIPLE PAYLOADS AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023065137-A1 | SITE-SPECIFIC GLYCOPROTEIN CONJUGATES AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-04-27 | — | — | WO | disclosed |
| EP-2966078-A2 | Inhibitors of histone deacetylase | MethylGene Inc. (CA) | 2016-01-13 | — | — | EP | disclosed |
| US-7897788-B2 | Indol-1-yl-acetic acid derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-03-01 | — | — | US | disclosed |
| EP-1740171-B1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-09 | — | — | EP | disclosed |
| US-20080027038-A1 | N-Acylated lipophilic amino acid derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2008-01-31 | — | — | US | disclosed |
| US-7279573-B2 | Amide derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20070208004-A1 | Indol-1-yl-acetic acid derivatives | ACTELION PHARMACEUTICALS, LTD. (CH) | 2007-09-06 | — | — | US | disclosed |
| EP-1021190-B1 | Amid derivatives as growth hormone release promotors | KAKEN PHARMA CO LTD (JP) | 2006-11-08 | — | — | EP | disclosed |
| EP-0875787-A1 | Method for reducing the substrate dependence of resist | Wako Pure Chemical Industries, Ltd. (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0579263-B1 | 1,4-Substituted piperidines as acetylchozinesterase inhibitors and their use for the treatment of Alzheimer's disease | EISAI CO LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1996005185-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-02-22 | — | — | WO | disclosed |
| EP-0673927-A1 | 4-[2-indanyl-1-one]alkylpiperidines as anticholinergic agents | Eisai Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0579263-A1 | 1,4-Substituted piperidines as acetylchozinesterase inhibitors and their use for the treatment of Alzheimer's disease | Eisai Co., Ltd. (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5100901-A | Treatment of Alzheimer*s disease | EISAI CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4895841-A | Cyclic amine compounds with activity against acetylcholinesterase | EISAI CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| US-4888335-A | HYPOTENSIVE AGENTS | MCNEILAB, INC. (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0296560-A2 | 1,4-Substituted piperidines as acetylcholinesterase inhibitors and their use for the treatment of Alzheimer's disease | Eisai Co., Ltd. (JP) | 1988-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208004-A1 | Indol-1-yl-acetic acid derivatives | IDO1, IDO2, AANAT | NPC1 1800/4885MAPK13 2988/4885MAPK12 2532/4885 |
| US-20080027038-A1 | N-Acylated lipophilic amino acid derivatives | GHRHR, NPPA, SSTR5 | NPC1 365/4885MAPK13 3094/4885MAPK12 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.