Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20871413 | 0.89 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL29335401 | 0.85 | BCHE (0.45) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL20871179 | 0.84 | CNR2 (0.40) | ALDH1A1BCHESLC6A4PYCR1 | |
| SCHEMBL20871275 | 0.84 | APLNR (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL20871173 | 0.83 | PYCR1 (0.54) | ALDH1A1TSHRBCHEL3MBTL1PYCR1 | |
| SCHEMBL22340945 | 0.82 | BCHE (0.56) | SMN1; SMN2APLNRBCHEHTTL3MBTL1 | |
| SCHEMBL22340949 | 0.76 | BCHE (0.62) | SMN1; SMN2ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL13286274 | 0.75 | BCHE (0.46) | ALDH1A1TSHRBCHETDP1 | |
| SCHEMBL20871412 | 0.74 | HTT (0.42) | SMN1; SMN2ALDH1A1APLNRHTTL3MBTL1 | |
| SCHEMBL20871187 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | Universite Paris-Saclay (FR) | 2021-06-15 | — | — | US | disclosed |
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | Universite Paris-Saclay (FR) | 2020-08-13 | — | — | US | disclosed |
| WO-2019063952-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIVERSITE PARIS-SUD (FR) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | ADH1C, ADH1A, ADH5 | SMN1; SMN2 2857/4885ALDH1A1 179/4885TSHR 1107/4885 |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | ADH1C, PNMT, ADH1A | SMN1; SMN2 2752/4885ALDH1A1 182/4885TSHR 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.