Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 18/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091833 | 0.97 | FAAH (0.70) | FAAH | |
| SCHEMBL2095422 | 0.95 | FAAH (0.72) | FAAH | |
| SCHEMBL2096010 | 0.95 | FAAH (0.72) | FAAH | |
| SCHEMBL2095676 | 0.95 | FAAH (0.72) | FAAH | |
| SCHEMBL11662947 | 0.93 | FAAH (0.68) | FAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2095653 | 0.87 | FAAH (0.65) | FAAH | |
| SCHEMBL2091634 | 0.86 | CYP1A2 (0.71) | FAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10338248 | 0.85 | ALDH1A1 (0.73) | FAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3223930 | 0.84 | LMNA (0.74) | FAAHSMN1; SMN2 | |
| SCHEMBL5218010 | 0.84 | GAA (0.64) | FAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507453-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507453-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| US-8053418-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2011-11-08 | — | — | US | disclosed |
| US-8053418-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20080300388-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-04 | — | — | US | disclosed |
| US-20080300388-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-04 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20070185135-A1 | Drug-Polymer Conjugates | PHARMAESSENTIA CORP. | 2007-08-09 | — | — | US | disclosed |
| US-4487713-A | HEAT TREATMENT WITH TITANIUM, TIN, ANTIMONY OR ZIRCONIUM COMPOUND | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-12-11 | — | — | US | disclosed |
| US-4081472-A | CATALYTIC, FROM A CARBAMATE | MITSUI TOATSU CHEMICALS INC. (JA) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | PWWP2B, BRWD1, BAZ1A | FAAH 4658/4885NPC1 2009/4885RAB9A 113/4885 |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | FAAH 3448/4885NPC1 3130/4885RAB9A 3153/4885 |
| US-20070185135-A1 | Drug-Polymer Conjugates | LNPEP, MSN, ANPEP | FAAH 1627/4885NPC1 1708/4885RAB9A 4234/4885 |
| US-20080300388-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | PWWP2B, BRWD1, BAZ1A | FAAH 4658/4885NPC1 2009/4885RAB9A 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.