Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IGF2R | P11717 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GJA1 | P17302 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.39 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.39 |
| ▸ | FGF1 | P05230 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964722 | 1.00 | L3MBTL1 (0.46) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL16866291 | 0.88 | AMY1A (0.41) | L3MBTL1IGF2RALDH1A1FGF1PTPN1 | |
| SCHEMBL25140762 | 0.85 | LGALS3 (0.51) | L3MBTL1MEN1KMT2AMAPTGJA1 | |
| SCHEMBL16263450 | 0.85 | L3MBTL1 (0.53) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL25140877 | 0.85 | L3MBTL1 (0.53) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL25140766 | 0.85 | L3MBTL1 (0.53) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL19781814 | 0.85 | L3MBTL1 (0.53) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL25140770 | 0.84 | L3MBTL1 (0.50) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL19480148 | 0.83 | IGF2R (0.46) | L3MBTL1IGF2RMEN1KMT2AMAPT | |
| SCHEMBL19480247 | 0.83 | IGF2R (0.46) | L3MBTL1IGF2RMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10960018-B2 | Methods and compounds for stimulating read-through of premature termination codons | THE UAB RESEARCH FOUNDATION (US) | 2021-03-30 | — | — | US | disclosed |
| US-20190125775-A1 | Methods and Compounds for Stimulating Read-Through of Premature Termination Codons | THE UAB RESEARCH FOUNDATION | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10960018-B2 | Methods and compounds for stimulating read-through of premature termination codons | UPF1, NUDT21, RNGTT | L3MBTL1 612/4885IGF2R 3716/4885MEN1 4577/4885 |
| US-20190125775-A1 | Methods and Compounds for Stimulating Read-Through of Premature Termination Codons | UPF1, NUDT21, RNGTT | L3MBTL1 612/4885IGF2R 3716/4885MEN1 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.