SCHEMBL20970973

SCHEMBL20970973

CCCN(C)CCc1c[nH]c2cccc(O)c12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 13/20 0.74
HTR2C P28335 9/20 0.74
HTR2B P41595 8/20 0.74
HTR1A P08908 2/20 0.74
HTR6 P50406 2/20 0.74
DRD1 P21728 1/20 0.74
HTR1D P28221 1/20 0.74
HTR1B P28222 1/20 0.74
HTR1E P28566 1/20 0.74
ADORA2A P29274 1/20 0.74
ADORA2B P29275 1/20 0.74
HTR7 P34969 1/20 0.74
DRD3 P35462 1/20 0.74
HTR5A P47898 1/20 0.74
GAA P10253 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633040 1.00 HTR2A (0.74) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL26965637 0.92 HTR2A (0.71) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL25008705 0.91 HTR2A (0.69) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL29504144 0.90 HTR1A (0.77) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL20970883 0.90 HTR1A (0.77) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL25008691 0.90 HTR2A (0.67) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL20970980 0.87 HTR1A (0.82) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL29633120 0.87 HTR1A (0.82) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL31188168 0.85 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6
Psilocin SCHEMBL194899 0.85 HTR2A (1.00) HTR2AHTR2CHTR2BHTR1AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618981-A1 COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE Remedi, Inc. (US) 2025-09-24 EP claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-20 US claimed
WO-2024108195-A1 COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE REMEDI, INC. (US) 2024-05-23 WO claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
EP-4313030-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS Terran Biosciences, Inc. (US) 2024-02-07 EP claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
WO-2022221942-A1 PREVENTION OF DRUG DIVERSION BETTERLIFE PHARMA INC. (CA) 2022-10-27 WO claimed
WO-2022212854-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2022-10-06 WO claimed
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-04-23 US disclosed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2026-04-02 US disclosed
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-05-20 US disclosed
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-03-11 US disclosed
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-03-11 US disclosed
US-20200179349-A1 Methods of Treating Food Allergy Conditions Palo Alto Investors LP 2020-06-11 US disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR2A 6/4885HTR2C 8/4885HTR2B 11/4885
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 11/4885HTR2C 6/4885HTR2B 9/4885
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS HTR1A, HTR2A, HTR3A HTR2A 2/4885HTR2C 5/4885HTR2B 11/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A HTR2A 14/4885HTR2C 42/4885HTR2B 28/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B HTR2A 19/4885HTR2C 12/4885HTR2B 9/4885
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness QPCT, SLC38A7, QPCTL HTR2A 2610/4885HTR2C 1076/4885HTR2B 3639/4885
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 11/4885HTR2C 6/4885HTR2B 9/4885
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 9/4885HTR2C 5/4885HTR2B 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.