Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32009 | 0.86 | CES1 (0.52) | SMN1; SMN2MAPTRAB9ANPC1CES1 | |
| Methane SCHEMBL28792690 | 0.84 | CES1 (0.50) | SMN1; SMN2MAPTRAB9ANPC1CES1 | |
| SCHEMBL29056504 | 0.83 | KIF11 (0.43) | KIF11SMN1; SMN2MAPTWDR5PTPN5 | |
| SCHEMBL29033193 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTWDR5MMP3BCL2L1 | |
| SCHEMBL28641168 | 0.78 | PARP10 (0.48) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13110605 | 0.76 | KIF11 (0.39) | KIF11LMNA | |
| SCHEMBL9414658 | 0.76 | TSHR (0.55) | SMN1; SMN2BCL2L1CES1ALDH1A1HDAC1 | |
| SCHEMBL9341838 | 0.75 | SMN1; SMN2 (0.48) | KIF11SMN1; SMN2MAPTWDR5MMP3 | |
| SCHEMBL19385678 | 0.75 | PLOD2 (0.45) | BCL2L1RAB9ANPC1CES1PTPN1 | |
| SCHEMBL685624 | 0.75 | MAPT (0.52) | KIF11SMN1; SMN2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149882-B | Gem-difluoroolefin-pyrroline compound and preparation method and application thereof | 西南医科大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-113024349-B | 3, 3-difluoro-1, 5-hexadiene compound and preparation method and application thereof | 南京工业大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113149882-A | Gem-difluoroolefin-pyrroline compound and preparation method and application thereof | 西南医科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-113024349-A | 3, 3-difluoro-1, 5-hexadiene compound and preparation method and application thereof | 南京工业大学 | 2021-06-25 | — | — | CN | disclosed |
| US-20190144469-A1 | METHOD FOR PREPARING DIFLUOROALLYLBORONATE AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144469-A1 | METHOD FOR PREPARING DIFLUOROALLYLBORONATE AND APPLICATION THEREOF | GABRA6, GABRP, GABBR2 | KIF11 3425/4885SMN1; SMN2 4225/4885MAPT 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.