Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889911 | 0.81 | CRHR1 (0.43) | CRHR1HSP90AA1HSP90AB1 | |
| SCHEMBL2098385 | 0.78 | RARA (0.39) | HCAR3CNR2 | |
| SCHEMBL2099560 | 0.75 | HCAR3 (0.43) | HCAR3HSP90AA1HSP90AB1 | |
| SCHEMBL10775421 | 0.73 | AOC3 (0.36) | — | |
| SCHEMBL2098893 | 0.73 | RARA (0.34) | — | |
| SCHEMBL2099746 | 0.73 | ALDH1A1 (0.41) | CRHR1HSP90AA1HSP90AB1 | |
| SCHEMBL9130944 | 0.73 | ALDH1A1 (0.49) | HSP90AA1CNR2 | |
| SCHEMBL3633710 | 0.71 | MELK (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL2098789 | 0.68 | GABRA1 (0.32) | — | |
| SCHEMBL3634001 | 0.68 | CYP1A1 (0.33) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163952-B2 | RAR receptor agonist ligands and use thereof in human medicine and cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-04-24 | — | — | US | disclosed |
| EP-2146951-B1 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RES & DEV (FR) | 2010-12-01 | — | — | EP | disclosed |
| US-20100261754-A1 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261754-A1 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | RARA, RARB, RARG | HCAR3 60/4885CRHR1 876/4885HSP90AA1 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.