SCHEMBL20985114

SCHEMBL20985114

CC(O)OC(C)NC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CAD P27708 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096450 0.80 FOLH1 (0.32) ALDH1A1
SCHEMBL22023061 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9001169 0.76
Acrylamide SCHEMBL20571033 0.76 TSHR (0.50) ALDH1A1
SCHEMBL10899226 0.75
SCHEMBL28926887 0.73 TSHR (0.40) NPC1ALDH1A1CAD
SCHEMBL1278056 0.73 TSHR (0.58) ALDH1A1
SCHEMBL28427630 0.71 TSHR (0.46) NPC1ALDH1A1CAD
SCHEMBL1228638 0.71 NPC1 (0.40) NPC1ALDH1A1CAD
SCHEMBL27662 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014064-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN TOPIX PHARMACEUTICALS INC (US) 2026-01-15 US disclosed
US-12440432-B2 Methods and compositions for treatment of skin TOPIX PHARMACEUTICALS, INC. (US) 2025-10-14 US disclosed
EP-4552650-A2 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN Topix Pharmaceuticals, Inc. (US) 2025-05-14 EP disclosed
EP-3713583-B1 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN TOPIX PHARMACEUTICALS INC (US) 2025-01-22 EP disclosed
US-20240108556-A1 SCAR TREATMENT COMPOSITION TOPIX PHARMACEUTICALS, INC. 2024-04-04 US disclosed
US-20240075112-A1 SCAR TREATMENT COMPOSITION TOPIX PHARMACEUTICALS, INC. 2024-03-07 US disclosed
EP-4251196-A1 SCAR TREATMENT COMPOSITION Topix Pharmaceuticals, Inc. (US) 2023-10-04 EP disclosed
EP-4251141-A1 SCAR TREATMENT COMPOSITION Topix Pharmaceuticals, Inc. (US) 2023-10-04 EP disclosed
CN-116782923-A Scar treatment composition 塔普克斯制药公司 2023-09-19 CN disclosed
CN-116710081-A Scar treatment composition 塔普克斯制药公司 2023-09-05 CN disclosed
US-20230173410-A1 RESTORING ACCUMULATED DGA WITH RECLAIMER SPARGE LINE SAUDI ARABIAN OIL COMPANY (SA) 2023-06-08 US disclosed
WO-2022115859-A1 SCAR TREATMENT COMPOSITION TOPIX PHARMACEUTICALS, INC. (US) 2022-06-02 WO disclosed
WO-2022115858-A1 SCAR TREATMENT COMPOSITION TOPIX PHARMACEUTICALS, INC. (US) 2022-06-02 WO disclosed
EP-3713583-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN Topix Pharmaceuticals, Inc. (US) 2020-09-30 EP disclosed
CN-111372595-A Methods and compositions for treating skin 塔普克斯制药公司 2020-07-03 CN disclosed
WO-2019104222-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN TOPIX PHARMACEUTICALS, INC. (US) 2019-05-31 WO disclosed
US-20190151214-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN TOPIX PHARMACEUTICALS INC (US) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108556-A1 SCAR TREATMENT COMPOSITION MMP1, MMP8, PLAT NPC1 2304/4885ALDH1A1 296/4885CAD 996/4885
US-20240075112-A1 SCAR TREATMENT COMPOSITION MMP1, MMP8, MMP2 NPC1 2426/4885ALDH1A1 173/4885CAD 597/4885
US-20260014064-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN CUTA, HAO2, SLC14A1 NPC1 851/4885ALDH1A1 291/4885CAD 1528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.