Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727777 | 1.00 | LMNA (0.35) | LMNASIGMAR1TRPA1MEN1KMT2A | |
| SCHEMBL8427323 | 0.79 | TDP1 (0.37) | SIGMAR1MEN1KMT2ATAAR1TSHR | |
| SCHEMBL11012885 | 0.76 | TDP1 (0.34) | LMNASIGMAR1TAAR1TSHRSLC18A2 | |
| SCHEMBL29403357 | 0.74 | TAAR1 (0.50) | LMNASIGMAR1TRPA1MEN1KMT2A | |
| SCHEMBL2099562 | 0.72 | SIGMAR1 (0.42) | LMNASIGMAR1TSHRRAB9A | |
| SCHEMBL2103828 | 0.72 | TSHR (0.38) | TSHRALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL2104457 | 0.71 | TAAR1 (0.39) | SIGMAR1MEN1KMT2ATAAR1TSHR | |
| SCHEMBL23521388 | 0.71 | L3MBTL1 (0.39) | GAAL3MBTL1 | |
| SCHEMBL2101246 | 0.71 | ADRA2A (0.38) | SIGMAR1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL31589987 | 0.71 | MAOA (0.32) | LMNASIGMAR1TAAR1TSHRSLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612756-B1 | Organosilicon compounds | NIPPON TELEGRAPH & TELEPHONE (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-5710301-A | Organosilicon compounds | NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0612756-A1 | Organosilicon compounds | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1994-08-31 | — | — | EP | disclosed |