SCHEMBL21022065

SCHEMBL21022065

C=C(CC)c1cc(C)ccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 2/20 0.37
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
ATM Q13315 1/20 0.35
P2RX7 Q99572 5/20 0.34
POLB P06746 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRB2 P47870 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076688 0.78 GABRA1 (0.41) RAB9AMEN1KMT2AKDM4ELMNA
SCHEMBL22672825 0.77 LOXL2 (0.37) RAB9AMEN1KMT2AKDM4EHPGD
SCHEMBL14404043 0.77 ALOX15 (0.45) RAB9AMAPTL3MBTL1ATMALDH1A1
SCHEMBL1024045 0.77 RAB9A (0.51) RAB9AMEN1KMT2AKDM4ELMNA
SCHEMBL25149154 0.74 CSNK2A1 (0.52) MEN1KMT2AKDM4EALDH1A1CSNK2A1
SCHEMBL21075951 0.74 PKM (0.39) MEN1KMT2AKDM4ELMNAHPGD
SCHEMBL8444340 0.74 CES2 (0.46) KMT2ALMNAHPGDPOLBALDH1A1
SCHEMBL5223648 0.74 CSNK2A1 (0.41) RAB9AMEN1KMT2AKDM4ELMNA
SCHEMBL20076629 0.73 CLCN2 (0.41) RAB9AMEN1KMT2AKDM4ELMNA
SCHEMBL16954239 0.73 GABRA1 (0.43) RAB9AMEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed