SCHEMBL2103073

SCHEMBL2103073

CC(C)([SiH2]c1ccccc1)C(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
RIPK1 Q13546 2/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2101734 0.79 MEN1 (0.33)
SCHEMBL2102686 0.79 HSP90AA1 (0.32) HSP90AA1MAPTGPR55
SCHEMBL2100788 0.75 SIGMAR1 (0.37) RIPK1MAPT
SCHEMBL2102750 0.75 PGR (0.34) RIPK1
SCHEMBL2102109 0.74 HTR2A (0.32) RIPK1
SCHEMBL2101130 0.74 HTR2A (0.32) TSHRRIPK1
SCHEMBL1254751 0.72 MAPK1 (0.36) TSHRMAPTMAPK1
Ethane SCHEMBL8430515 0.70 MAPK1 (0.35) TSHRMAPTMAPK1
SCHEMBL2103612 0.70 ADRA2B (0.40) RIPK1
SCHEMBL2103176 0.70 SIGMAR1 (0.39) RIPK1GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed