Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2099236 | 0.80 | CNR1 (0.35) | P4HBKDM4E | |
| SCHEMBL4703946 | 0.77 | P4HB (0.41) | P4HB | |
| SCHEMBL2102887 | 0.75 | ADORA2A (0.36) | NPY5RP4HBALDH1A1 | |
| SCHEMBL2101678 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL3606473 | 0.73 | KDM4E (0.33) | NPY5RKDM4EALDH1A1 | |
| SCHEMBL3606470 | 0.73 | KDM4E (0.33) | NPY5RKDM4EALDH1A1 | |
| SCHEMBL2100073 | 0.72 | POLB (0.38) | P4HBALDH1A1 | |
| SCHEMBL2102383 | 0.69 | RAB9A (0.49) | KDM4EALDH1A1 | |
| SCHEMBL9198990 | 0.67 | GABRA1 (0.44) | P4HBKDM4EALDH1A1 | |
| SCHEMBL3605331 | 0.67 | HPGD (0.35) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163770-B2 | Benzoxathiin derivative | MSD. K. K. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100168156-A1 | Novel Benzoxathiine Derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168156-A1 | Novel Benzoxathiine Derivative | XDH, GPR119, BRIX1 | NPY5R 46/4885P4HB 1226/4885KDM4E 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.