SCHEMBL21041374

SCHEMBL21041374

COc1cccc(N2c3ccccc3N(C)[C@H]2C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.43
▸ ALDH1A1 P00352 5/20 0.39
▸ MAPT P10636 4/20 0.39
▸ HPGD P15428 3/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ HTT P42858 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ ALOX12 P18054 2/20 0.39
▸ DRD2 P14416 3/20 0.38
▸ DRD3 P35462 2/20 0.38
▸ MEN1 O00255 2/20 0.36
▸ ALOX15 P16050 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA4 P22748 1/20 0.36
▸ CA7 P43166 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13681662 0.87 LMNA (0.47) LMNAALDH1A1MAPTHPGDKDM4E
SCHEMBL16420322 0.85 KDM4E (0.47) LMNAALDH1A1HPGDKDM4EHTT
SCHEMBL21041379 0.83 HSD11B1 (0.40) LMNAALDH1A1MAPTHPGDKDM4E
SCHEMBL12092106 0.80 ALDH1A1 (0.43) LMNAALDH1A1MAPTHPGDKDM4E
SCHEMBL16421536 0.80 ALDH1A1 (0.43) LMNAALDH1A1MAPTHPGDKDM4E
SCHEMBL16420329 0.78 KDM4E (0.41) ALDH1A1HPGDKDM4EGAAALOX12
SCHEMBL16769702 0.78 KDM4E (0.41) ALDH1A1HPGDKDM4EGAAALOX12
SCHEMBL16420323 0.75 KDM4E (0.40) LMNAALDH1A1HPGDKDM4EHTT
SCHEMBL22199127 0.75 KDM4E (0.33) ALDH1A1HPGDKDM4EGAAALOX12
SCHEMBL9891023 0.74 ALDH1A1 (0.42) LMNAALDH1A1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11758804-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 — — US disclosed
US-11758804-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 — — US disclosed
US-10301338-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11758804-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 LMNA 1814/4885ALDH1A1 102/4885MAPT 2043/4885
US-10301338-B2 Organic electroluminescent materials and devices PNMT, TAAR5, TST LMNA 3767/4885ALDH1A1 2954/4885MAPT 691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback