Sugi Predict

Sugi Predict / Compounds / SCHEMBL2106698

SCHEMBL2106698

SCHEMBL2106698

C/C(=C\CCCC(C)(C)O)c1cccc(/C=C/c2cc(O)cc(O)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LCK P06239 1/20 0.44
▸ KDM1A O60341 1/20 0.44
▸ PTGS1 P23219 5/20 0.40
▸ PTGS2 P35354 4/20 0.40
▸ TTR P02766 4/20 0.39
▸ P4HB P07237 3/20 0.38
▸ KDM4E B2RXH2 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ USP2 O75604 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ TRPV1 Q8NER1 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ ABL1 P00519 1/20 0.36
▸ BCR P11274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2106699 1.00 LCK (0.44) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2107065 0.81 LCK (0.50) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2107064 0.81 LCK (0.50) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2106706 0.77 LCK (0.49) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2106702 0.77 LCK (0.49) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2107876 0.74 HMGCR (0.57) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2106613 0.74 LCK (0.49) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2106612 0.74 LCK (0.49) LCKKDM1APTGS1PTGS2TTR
SCHEMBL2107875 0.74 HMGCR (0.57) LCKKDM1APTGS1PTGS2TTR
SCHEMBL6155055 0.73 HMGCR (0.56) LCKKDM1APTGS1PTGS2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 — — EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 — — US claimed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 — — US disclosed
EP-2836187-B1 SELF-STANDING COSMETIC SHEET OREAL (FR) 2021-12-08 — — EP disclosed
US-20180235849-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2018-08-23 — — US disclosed
US-9949897-B2 Self-standing cosmetic sheet L'OREAL (FR) 2018-04-24 — — US disclosed
US-20150209243-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2015-07-30 — — US disclosed
EP-1658838-B1 Emulsification system for use in cosmetics ORÉAL L (FR) 2014-07-02 — — EP disclosed
US-8158136-B2 Emulsification system for use in cosmetics L'ORÉAL (FR) 2012-04-17 — — US disclosed
US-20070025939-A1 cosmetic compositions containing hydroquinone and various sunscreen agents L'OREAL S.A. (FR) 2007-02-01 — — US disclosed
US-20070025937-A1 Cosmetic compositions containing hydroquinone L'OREAL S.A. (FR) 2007-02-01 — — US disclosed
US-20060039936-A1 Emulsification system for use in cosmetics L'OREAL (FR) 2006-02-23 — — US disclosed
US-20050169945-A1 Composition for protecting keratin material, process of making, uses thereof L'OREAL (FR) 2005-08-04 — — US disclosed
EP-1559398-A1 Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins L'OREAL (FR) 2005-08-03 — — EP disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 — — EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 — — US disclosed
US-20020197289-A1 Compositions and methods for combating the appearance of ageing L'OREAL (FR) 2002-12-26 — — US disclosed
EP-1262168-A1 Composition containing fibres to combat the skin aging process L'OREAL (FR) 2002-12-04 — — EP disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 — — EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020197289-A1 Compositions and methods for combating the appearance of ageing CYP24A1, CYP27B1, CYP2R1 LCK 4528/4885KDM1A 2885/4885PTGS1 2838/4885
US-20070025939-A1 cosmetic compositions containing hydroquinone and various sunscreen agents DHX15, HSPA4L, DDX3X LCK 4194/4885KDM1A 1804/4885PTGS1 3589/4885
US-20150209243-A1 SELF-STANDING COSMETIC SHEET CUTA, SUCLG1, SIGLEC7 LCK 2403/4885KDM1A 990/4885PTGS1 1730/4885
US-20180235849-A1 SELF-STANDING COSMETIC SHEET CUTA, DSG1, SUCLG1 LCK 2789/4885KDM1A 1865/4885PTGS1 1771/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 LCK 2789/4885KDM1A 1865/4885PTGS1 1771/4885
US-20050169945-A1 Composition for protecting keratin material, process of making, uses thereof KRT18, PROC, CUTA LCK 3497/4885KDM1A 1989/4885PTGS1 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.