Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 4/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21066980 | 0.99 | SORT1 (0.46) | SORT1GIGYF2ITGB1ITGA4LY6K | |
| SCHEMBL19952732 | 0.89 | ITGB1 (0.47) | SORT1GIGYF2ITGB1ITGA4LY6K | |
| SCHEMBL19952750 | 0.89 | LOXL2 (0.54) | GIGYF2ITGB1ITGA4TDP1LOX | |
| SCHEMBL19952637 | 0.89 | GIGYF2 (0.46) | SORT1GIGYF2ITGB1ITGA4LY6K | |
| SCHEMBL19952710 | 0.89 | LOXL2 (0.53) | GIGYF2ITGB1ITGA4TDP1LOX | |
| Hydrochloric Acid SCHEMBL19952655 | 0.89 | LOXL2 (0.54) | GIGYF2ITGB1ITGA4TDP1LOX | |
| Hydrochloric Acid SCHEMBL19952640 | 0.88 | LOXL2 (0.53) | GIGYF2ITGB1ITGA4TDP1LOX | |
| SCHEMBL21067002 | 0.88 | SORT1 (0.46) | SORT1GIGYF2ITGB1ITGA4LY6K | |
| SCHEMBL19960753 | 0.87 | GIGYF2 (0.46) | SORT1GIGYF2ITGB1ITGA4LY6K | |
| SCHEMBL19952704 | 0.84 | LOXL2 (0.52) | SORT1LY6KLOXLOXL2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | LOXL2, LOXL1, LOXL3 | SORT1 1850/4885GIGYF2 2254/4885ITGB1 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.