Sugi Predict

Sugi Predict / Compounds / SCHEMBL2107458

SCHEMBL2107458

SCHEMBL2107458

CCCOc1cccc(Oc2ccccc2C(=COC)C(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.47
▸ LMNA P02545 4/20 0.45
▸ MAPT P10636 1/20 0.45
▸ LTB4R Q15722 1/20 0.45
▸ LTB4R2 Q9NPC1 1/20 0.45
▸ KDM4E B2RXH2 7/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ GAA P10253 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ ERN1 O75460 1/20 0.42
▸ TDP1 Q9NUW8 2/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ MTNR1B P49286 1/20 0.41
▸ PLA2G4B P0C869 1/20 0.40
▸ ACACB O00763 1/20 0.40
▸ ACACA Q13085 1/20 0.40
▸ MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107453 1.00 KMT2A (0.47) KMT2ALMNAMAPTLTB4RLTB4R2
SCHEMBL2849713 1.00 KMT2A (0.47) KMT2ALMNAMAPTLTB4RLTB4R2
SCHEMBL2107695 0.92 LMNA (0.48) LMNAMAPTLTB4RLTB4R2KDM4E
SCHEMBL30052608 0.92 LMNA (0.48) LMNAMAPTLTB4RLTB4R2KDM4E
SCHEMBL2851184 0.92 LMNA (0.48) LMNAMAPTLTB4RLTB4R2KDM4E
SCHEMBL2107700 0.92 LMNA (0.48) LMNAMAPTLTB4RLTB4R2KDM4E
SCHEMBL204215 0.90 LMNA (0.44) KMT2ALMNAMAPTLTB4RLTB4R2
SCHEMBL29359005 0.90 LMNA (0.44) KMT2ALMNAMAPTLTB4RLTB4R2
SCHEMBL2107457 0.89 KMT2A (0.50) KMT2ALMNAMAPTLTB4RLTB4R2
SCHEMBL2849718 0.89 KMT2A (0.50) KMT2ALMNAMAPTLTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 — — US disclosed
US-20240041028-A1 DELIVERY SYSTEM FOR PLANT PROTECTION OMYA INTERNATIONAL AG (CH) 2024-02-08 — — US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 — — US disclosed
EP-4271185-A1 DELIVERY SYSTEM FOR PLANT PROTECTION Omya International AG (CH) 2023-11-08 — — EP disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 — — US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 — — EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 — — EP disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 — — EP disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 — — US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 — — US disclosed
US-5990043-A COMPRISES AT LEAST ONE INSECTICIDE SELECTED FROM TRIFLUMURON, FLUFENOXURON, FLUCYCLOXURON, HEXAFLUMURON, AND OTHERS; A CARRIER AND BINDER; PROTECTS ITEMS SUCH AS SHIP HULLS IN BRACKISH OR SEAWATER FROM BARNICLE INFESTATIONS BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 — — US disclosed
US-5972971-A WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX BAYER AKTIENGESELLSCHAFT (DE) 1999-10-26 — — US disclosed
EP-0865436-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AG (DE) 1998-09-23 — — EP disclosed
US-5767137-A FOR INDUSTRIAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-16 — — US disclosed
WO-1997020830-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-06-12 — — WO disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 — — EP disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 — — US disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 KMT2A 2752/4885LMNA 3444/4885MAPT 3320/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 KMT2A 3894/4885LMNA 4247/4885MAPT 4642/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG KMT2A 4259/4885LMNA 4274/4885MAPT 4168/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 KMT2A 3061/4885LMNA 4252/4885MAPT 2674/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 KMT2A 4113/4885LMNA 3731/4885MAPT 3764/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 KMT2A 2043/4885LMNA 4022/4885MAPT 3334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.