SCHEMBL2108886

SCHEMBL2108886

COC(=O)c1ccc(CNS(C)(=O)=O)cc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.51
GAA P10253 1/20 0.49
TP53 P04637 1/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
CYP1A2 P05177 1/20 0.38
CNR2 P34972 1/20 0.36
HDAC1 Q13547 1/20 0.35
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116828 0.99 CDK1 (0.52) CDK1GAATP53GLAMAPT
SCHEMBL19283719 0.99 CDK1 (0.52) CDK1GAATP53GLAMAPT
SCHEMBL6443045 0.95 CDK1 (0.49) CDK1GAATP53GLAMAPT
SCHEMBL21585569 0.92 CDK1 (0.51) CDK1GAATP53GLAMAPT
SCHEMBL121017 0.91 CDK1 (0.52) CDK1GAATP53GLAMAPT
SCHEMBL13370005 0.91 CDK1 (0.52) CDK1GAATP53GLAMAPT
SCHEMBL6910814 0.90 CDK1 (0.50) CDK1GAATP53GLAMAPT
SCHEMBL5847082 0.89 CDK1 (0.51) CDK1GAATP53GLAMAPT
SCHEMBL25397187 0.88 CDK1 (0.49) CDK1GAATP53GLAMAPT
SCHEMBL7933527 0.87 CDK1 (0.52) CDK1GAATP53GLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114025609-A High spread ULV formulations for herbicides 拜耳公司 2022-02-08 CN claimed
EP-3616514-A1 TERNARY HERBICIDE COMBINATIONS COMPRISING TWO SULFONLYUREAS Bayer CropScience Aktiengesellschaft (DE) 2020-03-04 EP claimed
EP-3613287-A1 TERNARY HERBICIDE COMBINATIONS COMPRISING TWO SULFONLYUREAS Bayer CropScience Aktiengesellschaft (DE) 2020-02-26 EP claimed
US-20190174763-A1 TERNARY HERBICIDE COMBINATIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-06-13 US claimed
US-10258044-B2 Ternary herbicide combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-16 US claimed
US-20170042157-A1 HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-16 US claimed
US-20160174560-A1 Ternary Herbicide Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-23 US claimed
EP-3030078-A1 TERNARY HERBICIDE COMBINATIONS COMPRISING TWO SULFONLYUREAS Bayer CropScience Aktiengesellschaft (DE) 2016-06-15 EP claimed
WO-2015018812-A1 TERNARY HERBICIDE COMBINATIONS COMPRISING TWO SULFONLYUREAS BAYER CROPSCIENCE AG (DE) 2015-02-12 WO claimed
US-8901036-B2 Combinations of phenylsulfonylurea herbicides and safeners BAYER CROPSCIENCE AG (DE) 2014-12-02 US claimed
US-8158558-B2 Synergistic mixture of a mesosulfuron or iodinosulfuron ester of given formula, with another herbicide selected from a list of 23 that includes picolinafen, flucarbazone, procarbazone and cinidon-ethyl; controlling weeds in monocot crops BAYER CROPSCIENCE GMBH (DE) 2012-04-17 US claimed
EP-1951049-B1 DIFLUFENICAN-CONTAINING OIL SUSPENSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2011-08-10 EP claimed
US-20090156400-A1 HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS BIERINGER 2009-06-18 US claimed
EP-1411767-B1 HERBICIDE COMBINATIONS COMPRISING SPECIAL SULPHONYL UREAS BAYER CROPSCIENCE AG (DE) 2008-12-31 EP claimed
US-20080287296-A1 Herbicide Combinations Comprising Specific Sulfonylureas BAYER CROPSCIENCE AG (DE) 2008-11-20 US claimed
EP-1482799-B1 HERBICIDE COMBINATIONS WITH SPECIAL SULFONYLUREAS BAYER CROPSCIENCE AG (DE) 2008-05-21 EP claimed
US-6743754-B2 A SULFONYLUREA AND ONE OR MORE SURFACTANTS COMPRISING AS STRUCTURAL ELEMENT AT LEAST 10 ALKYLENE OXIDE UNITS. AVENTIS CROPSCIENCE GMBH (DE) 2004-06-01 US claimed
US-20030186816-A1 For controlling undesired plant growth BAYER CROPSCIENCE GMBH (DE) 2003-10-02 US claimed
US-6573217-B2 Herbicidal compositions AVENTIS CROPSCIENCE GMBH (DE) 2003-06-03 US claimed
US-20030060367-A1 Herbicide combinations comprising specific sulfonylureas BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-03-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060367-A1 Herbicide combinations comprising specific sulfonylureas ADORA2B, CHRM2, B2M CDK1 1186/4885GAA 3313/4885TP53 2543/4885
US-20190174763-A1 TERNARY HERBICIDE COMBINATIONS DDT, DHX35, DDX41 CDK1 306/4885GAA 3502/4885TP53 1658/4885
US-20170042157-A1 HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS GSTM2, GSTM1, CHRM2 CDK1 2521/4885GAA 991/4885TP53 2139/4885
US-20080287296-A1 Herbicide Combinations Comprising Specific Sulfonylureas SLC16A3, SLC16A7, SLC16A1 CDK1 1449/4885GAA 2842/4885TP53 3426/4885
US-20160174560-A1 Ternary Herbicide Combinations DDT, DHX35, DDX41 CDK1 306/4885GAA 3502/4885TP53 1658/4885
US-10258044-B2 Ternary herbicide combinations DDT, DHX35, DDX41 CDK1 306/4885GAA 3502/4885TP53 1658/4885
US-20030186816-A1 For controlling undesired plant growth MTX2, DDT, METAP2 CDK1 947/4885GAA 2206/4885TP53 3678/4885
US-20090156400-A1 HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS ADORA3, ADORA2B, CHRM2 CDK1 1618/4885GAA 2829/4885TP53 2551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.