Mecarbinate

Mecarbinate

SCHEMBL2109102

CCOC(=O)c1c(C)n(C)c2ccc(O)cc12

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.72
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
GAA P10253 4/20 0.69
KDM4E B2RXH2 4/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
HSD17B10 Q99714 2/20 0.69
ALDH1A1 P00352 2/20 0.69
HPGD P15428 2/20 0.69
TSHR P16473 1/20 0.69
MAPT P10636 3/20 0.64
PKM P14618 2/20 0.64
POLB P06746 1/20 0.64
ALOX5 P09917 4/20 0.62
ALOX15 P16050 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mecarbinate SCHEMBL29380431 1.00 LMNA (0.72) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL22478566 0.87 ALDH1A1 (0.67) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL6795778 0.85 ALOX5 (0.68) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL21954348 0.84 ALDH1A1 (0.63) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL9557007 0.83 SMN1; SMN2 (0.76) LMNAKDM4ESMN1; SMN2HSD17B10ALDH1A1
SCHEMBL30875172 0.83 SMN1; SMN2 (0.76) LMNAKDM4ESMN1; SMN2HSD17B10ALDH1A1
SCHEMBL30657206 0.83 MEN1 (1.00) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL6315596 0.83 MEN1 (1.00) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL13576495 0.83 KMT2A (0.82) LMNAMEN1KMT2AGAAKDM4E
SCHEMBL29429164 0.81 POLB (0.74) LMNAMEN1KMT2AGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US claimed
CN-116901484-A Preparation process of environment-friendly wear-resistant and high-temperature-resistant composite clutch facing 来安县隆华摩擦材料有限公司 2023-10-20 CN claimed
CN-116515275-A Chopped glass fiber plastic alloy and preparation method thereof 安徽捷云新材料科技有限公司 2023-08-01 CN claimed
CN-116217461-A Chalcone derivative containing indole structure and preparation method and application thereof 贵州大学 2023-06-06 CN claimed
US-20220175742-A1 COLLAGEN P4H1 INHIBITOR AND ITS USE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2022-06-09 US claimed
CN-111269168-B Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2022-04-01 CN claimed
WO-2021041942-A1 COLLAGEN P4H1 INHIBITOR AND ITS USE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2021-03-04 WO claimed
CN-111533677-A Method for synthesizing arbidol hydrochloride intermediate 大连万福制药有限公司 2020-08-14 CN claimed
CN-111269168-A Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2020-06-12 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
CN-103113287-A Method for preparing mecarbinate (1,2-dimethyl-5hydroxy-1H-indol-3-ethyl carboxylate) SHAANXI PUCHENG WANDE SCIENCE & TECHNOLOGY CO LTD 2013-05-22 CN claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-12564578-B2 Collagen P4H1 inhibitor and its use UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2026-03-03 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564578-B2 Collagen P4H1 inhibitor and its use P4HA1, P4HTM, COLGALT1 LMNA 2426/4885MEN1 4242/4885KMT2A 1900/4885
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME SQSTM1, BECN1, CUTA LMNA 38/4885MEN1 3254/4885KMT2A 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.