Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 6/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093972 | 0.88 | CHRM3 (0.35) | GPBAR1 | |
| SCHEMBL21094405 | 0.87 | PKM (0.40) | PTGESALDH1A1MGLL | |
| SCHEMBL21094395 | 0.84 | ALDH1A1 (0.38) | TSHRALDH1A1ELANE | |
| SCHEMBL21094093 | 0.79 | MAPT (0.39) | PTGESGPBAR1 | |
| SCHEMBL21093670 | 0.76 | TRPM8 (0.43) | TSHRALDH1A1 | |
| SCHEMBL21093976 | 0.73 | TSHR (0.38) | PTGESTACR1TSHRGPBAR1UBE2M | |
| SCHEMBL21094393 | 0.71 | NPC1 (0.40) | — | |
| SCHEMBL21094397 | 0.68 | NPC1 (0.39) | — | |
| SCHEMBL21094410 | 0.66 | NPC1 (0.40) | — | |
| SCHEMBL21094386 | 0.66 | RIPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |