Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093670 | 0.90 | TRPM8 (0.43) | TRPM8ATMLMNANPSR1L3MBTL1 | |
| SCHEMBL21094395 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2CHRM5CHRM1RAB9ANPC1 | |
| SCHEMBL21094093 | 0.88 | MAPT (0.39) | TRPM8HCAR2SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL21093972 | 0.88 | CHRM3 (0.35) | PKMLMNADHODHMAPT | |
| SCHEMBL21093964 | 0.87 | PTGES (0.38) | MGLLPTGESALDH1A1 | |
| SCHEMBL21094393 | 0.84 | NPC1 (0.40) | TRPM8ATMSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21094397 | 0.81 | NPC1 (0.39) | TRPM8ATMSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21094386 | 0.79 | RIPK1 (0.38) | TRPM8ATMRAB9ANPC1 | |
| SCHEMBL21094410 | 0.79 | NPC1 (0.40) | TRPM8ATMSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21094394 | 0.79 | NPC1 (0.41) | TRPM8ATMRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |