Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.34 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093964 | 0.88 | PTGES (0.38) | GPBAR1 | |
| SCHEMBL21094093 | 0.88 | MAPT (0.39) | GPBAR1LMNAMAPTKMT2A | |
| SCHEMBL21094405 | 0.88 | PKM (0.40) | LMNAMAPTDHODHPKM | |
| SCHEMBL21094395 | 0.85 | ALDH1A1 (0.38) | CHRM3 | |
| SCHEMBL21093670 | 0.77 | TRPM8 (0.43) | CHRM3LMNAMAPTKMT2A | |
| SCHEMBL21093967 | 0.73 | PKM (0.37) | GPBAR1KMT2APKM | |
| SCHEMBL21094101 | 0.71 | KIF11 (0.41) | MAPT | |
| SCHEMBL28907110 | 0.71 | XPO1 (0.44) | CHRM3XPO1LMNAMAPTKMT2A | |
| SCHEMBL21094393 | 0.71 | NPC1 (0.40) | — | |
| SCHEMBL21094102 | 0.69 | KIF11 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |