SCHEMBL2109929

SCHEMBL2109929

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.54
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPSR1 Q6W5P4 3/20 0.49
NPC1 O15118 2/20 0.49
ALDH1A1 P00352 2/20 0.49
RAB9A P51151 2/20 0.49
GAA P10253 1/20 0.48
TGM2 P21980 1/20 0.47
TDP1 Q9NUW8 4/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
ATM Q13315 1/20 0.46
POLB P06746 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CA1 P00915 5/20 0.44
CA2 P00918 5/20 0.44
CA12 O43570 3/20 0.43
CA9 Q16790 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13041077 1.00 MGLL (0.54) MGLLMAPTSMN1; SMN2NPSR1NPC1
SCHEMBL29400674 1.00 MGLL (0.54) MGLLMAPTSMN1; SMN2NPSR1NPC1
SCHEMBL31519043 0.97 MGLL (0.54) MGLLMAPTSMN1; SMN2NPSR1NPC1
SCHEMBL14299860 0.94 MGLL (0.49) MGLLMAPTSMN1; SMN2NPSR1NPC1
SCHEMBL18560008 0.90 KLK7 (0.57) MAPTTGM2CA1CA2KLK7
SCHEMBL7302025 0.90 TGM2 (0.56) MGLLMAPTNPSR1TGM2TDP1
SCHEMBL13041082 0.90 KLK7 (0.57) MAPTTGM2CA1CA2KLK7
SCHEMBL30684686 0.89 MGLL (0.58) MGLLMAPTSMN1; SMN2NPSR1NPC1
SCHEMBL10866363 0.89 MAPT (0.49) MGLLMAPTSMN1; SMN2NPSR1NPC1
SCHEMBL3401322 0.89 MGLL (0.59) MGLLMAPTNPSR1TGM2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3915587-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2026-03-25 EP disclosed
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2026-01-01 US disclosed
EP-4647436-A2 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES Sapreme Technologies B.V. (NL) 2025-11-12 EP disclosed
US-12453782-B2 Antibody-oligonucleotide conjugate SAPREME TECHNOLOGIES B.V. (NL) 2025-10-28 US disclosed
EP-3897735-B1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECH BV (NL) 2025-10-22 EP disclosed
US-20250302983-A1 Saponin Conjugates SAPREME TECHNOLOGIES B.V. (NL) 2025-10-02 US disclosed
US-12421276-B2 Methods of treating neurodegenerative disease with substituted n-hexanoic-l-tyrosine-l-isoleucine-(6)-aminohexanoic amide analogues ATHIRA PHARMA, INC. (US) 2025-09-23 US disclosed
EP-4588523-A2 IMPROVED CELL-TARGETING BINDING MOLECULE Sapreme Technologies B.V. (NL) 2025-07-23 EP disclosed
US-20250195682-A1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECHNOLOGIES B.V. (NL) 2025-06-19 US disclosed
EP-4241847-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2025-06-04 EP disclosed
WO-2011140376-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS PROLYNX LLC (US) 2011-11-10 WO disclosed
US-20090269298-A1 AGENT FOR THE PREVENTION AND TREATMENT OF SEXUALLY TRANSMITTED DISEASES-I STARPHARMA PTY LTD. 2009-10-29 US disclosed
US-7589056-B2 Agent for the prevention and treatment of sexually transmitted diseases-I STARPHARMA PTY. LTD. (AU) 2009-09-15 US disclosed
EP-1399499-B1 AGENT FOR THE PREVENTION AND TREATMENT OF SEXUALLY TRANSMITTED DISEASES-I STARPHARMA PTY LTD (AU) 2009-03-18 EP disclosed
US-20050008611-A1 Agent for the prevention and treatment of sexually transmitted diseases-I STARPHARMA PTY LTD (AU) 2005-01-13 US disclosed
EP-0636028-B1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING AN AMPHIPHATIC CATIONIC PEPTIDE UNIV CALIFORNIA (US) 2004-03-03 EP disclosed
EP-1236473-A2 Self-assembling polynucleotide delivery system THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-09-04 EP disclosed
US-4410688-A POLYAMIDES FROM DIAMINOCARBOXYLIC ACIDS ALLIED CORPORATION (US) 1983-10-18 US disclosed
US-4360646-A Preparation of lysine based macromolecular highly branched homogeneous compound ALLIED CORPORATION (US) 1982-11-23 US disclosed
US-4289872-A SURFACE MODIFYING AGENTS, METAL CHELATING AGENTS, SUBSTRATES FOR DRUGS ALLIED CORPORATION (US) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302983-A1 Saponin Conjugates EPCAM, CD47, SHBG MGLL 4483/4885MAPT 4204/4885SMN1; SMN2 4094/4885
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, FCGR3B MGLL 4330/4885MAPT 3753/4885SMN1; SMN2 3134/4885
US-12421276-B2 Methods of treating neurodegenerative disease with substituted n-hexanoic-l-tyrosine-l-isoleucine-(6)-aminohexanoic amide analogues AADAT, ABAT, IAPP MGLL 707/4885MAPT 48/4885SMN1; SMN2 30/4885
US-12453782-B2 Antibody-oligonucleotide conjugate CD40, FCGR1A, TNFSF10 MGLL 3151/4885MAPT 4452/4885SMN1; SMN2 3219/4885
US-20050008611-A1 Agent for the prevention and treatment of sexually transmitted diseases-I DNPEP, CTSA, TLR1 MGLL 1559/4885MAPT 2210/4885SMN1; SMN2 3197/4885
US-20250195682-A1 IMPROVED CELL-TARGETING BINDING MOLECULE EPCAM, CD47, CD74 MGLL 4339/4885MAPT 4039/4885SMN1; SMN2 3978/4885
US-20090269298-A1 AGENT FOR THE PREVENTION AND TREATMENT OF SEXUALLY TRANSMITTED DISEASES-I DNPEP, CTSA, TLR1 MGLL 1559/4885MAPT 2210/4885SMN1; SMN2 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.