SCHEMBL21137914

SCHEMBL21137914

CCCC(=O)N[C@H]1C(C)O[C@H](COC(=O)Sc2ccc(C)cc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 1/20 0.35
▸ HPGD P15428 3/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ LGALS3 P17931 1/20 0.32
▸ CA1 P00915 2/20 0.31
▸ CA2 P00918 2/20 0.31
▸ CA9 Q16790 2/20 0.31
▸ SSTR4 P31391 2/20 0.31
▸ SSTR5 P35346 2/20 0.31
▸ GAA P10253 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30
▸ TRIP13 Q15645 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835069 0.91 PYGB (0.36) PYGBHPGDKDM4ELGALS3SSTR4
SCHEMBL25836026 0.80 PYGB (0.33) PYGBHPGDKDM4EGAAHSD17B10
SCHEMBL25959218 0.80 PYGB (0.35) PYGBHPGDKDM4EGAAHSD17B10
SCHEMBL21137906 0.78 PYGB (0.44) PYGBCA1CA2CA9GAA
SCHEMBL21138213 0.75 LMNA (0.37) PYGBHPGDKDM4ESSTR4SSTR5
SCHEMBL21137875 0.74 PYGB (0.40) PYGBGAA
SCHEMBL25835981 0.73 SSTR3 (0.35) PYGBCA1CA2CA9SSTR4
SCHEMBL21138776 0.73 ALDH1A1 (0.35) PYGBCA1CA2CA9SSTR4
SCHEMBL25957856 0.73 ACACB (0.34) PYGBSSTR4SSTR5
SCHEMBL21138642 0.73 L3MBTL1 (0.45) HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA PYGB 760/4885HPGD 192/4885KDM4E 3760/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA PYGB 760/4885HPGD 192/4885KDM4E 3760/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA PYGB 601/4885HPGD 242/4885KDM4E 3651/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA PYGB 601/4885HPGD 242/4885KDM4E 3651/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA PYGB 601/4885HPGD 242/4885KDM4E 3651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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